Description

Inosine 5'-(Tetrahydrogen Triphosphate), 2',3'-Dideoxy-, Trilithium Salt is a chemically modified nucleoside triphosphate analog, specifically designed for research and development applications. This compound is critical for biochemical studies involving DNA/RNA synthesis, polymerase mechanisms, and antiviral research. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on nucleotide-based therapeutics and molecular biology.

Application

• Biochemical Research: As a substrate analog for studying the activity and inhibition of viral reverse transcriptase and other DNA/RNA polymerases.
• Antiviral Drug Development: Serves as a key intermediate or reference standard in the synthesis and evaluation of nucleoside analog prodrugs.
• Enzymology Studies: Used to investigate enzyme kinetics, fidelity, and the incorporation mechanisms of modified nucleotides.
• Molecular Biology: Potential use in specialized in vitro transcription or sequencing applications requiring chain-terminating nucleotides.
• Diagnostic Assay Development: Can be incorporated into probes or used in the development of assays for viral load detection.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	Inosine 5'-(Tetrahydrogen Triphosphate), 2',3'-Dideoxy-, Trilithium Salt
CAS No.	93858-64-1
Molecular Formula	C10H12Li3N4O12P3
Molecular Weight	528.02 g/mol (anhydrous basis)
Synonyms	2',3'-Dideoxyinosine 5'-triphosphate trilithium salt; ddITP, Trilithium salt; 2',3'-Dideoxy-ITP Li3 salt; Inosine, 2',3'-dideoxy-, 5'-(tetrahydrogen triphosphate), trilithium salt; ddInosine triphosphate; 2',3'-Dideoxyinosine-5'-triphosphate; Trilithium 2',3'-dideoxyinosine-5'-triphosphate
EINECS	Contact for details

Quality Control

Our Inosine 5'-(Tetrahydrogen Triphosphate), 2',3'-Dideoxy-, Trilithium Salt is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent internal quality standards and can provide material tailored to specific research-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, desiccate at low temperature. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤5.0%
pH (1% Solution)	6.0 - 8.0
Endotoxin	<10 EU/mg (if specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.