Description

2'-Deoxyuridine 5'-Triphosphate Tetralithium Salt is a high-purity nucleotide essential for molecular biology research and diagnostic applications. Its primary value lies in its role as a substrate for DNA polymerases, enabling precise enzymatic synthesis and analysis. This compound is critically needed by biotechnology companies, academic research institutions, and diagnostic kit manufacturers for applications in PCR, DNA sequencing, and mutagenesis studies.

Application

• Molecular Biology Research: Essential substrate for DNA polymerases in enzymatic DNA synthesis, PCR (Polymerase Chain Reaction), and site-directed mutagenesis.
• Next-Generation Sequencing (NGS): Used in sequencing-by-synthesis platforms as one of the natural nucleotide triphosphates for template-directed incorporation.
• Diagnostic Assay Development: A key component in the formulation of reagents for clinical diagnostic tests, including viral load detection and genetic screening.
• Biochemical Studies: Employed in enzyme kinetics studies to investigate the activity and fidelity of various DNA polymerases and reverse transcriptases.
• Antiviral Research: Serves as a reference compound and substrate in studies targeting viral DNA replication enzymes.
• Labeling and Detection: Can be used as a precursor for the synthesis of labeled nucleotides (e.g., fluorescent, biotinylated) for probe generation.

Basic Information

Item	Details
Product Name	2'-Deoxyuridine 5'-Triphosphate Tetralithium Salt
CAS No.	93858-62-9
Molecular Formula	C9H11Li4N2O14P3
Molecular Weight	508.01 g/mol (anhydrous basis)
Synonyms	dUTP, Tetralithium Salt; 2'-Deoxyuridine-5'-triphosphate lithium salt; Deoxyuridine triphosphate; dUTP Li4; 5'-dUTP; dUridine-5'-triphosphate; (2'R)-2'-Deoxy-5'-O-[(hydroxy{[(hydroxy(phosphonooxy)phosphoryl]oxy})phosphoryl]uridine tetralithium salt
EINECS	Contact for details

Quality Control

Our 2'-Deoxyuridine 5'-Triphosphate Tetralithium Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for sensitive applications. Each lot is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, desiccate. Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Enzymatic)	≥ 90%
pH (1% Solution)	6.5 - 7.5
Water Content (KF)	≤ 5.0 %
Endotoxin (LAL)	< 10 EU/mg
Filter Sterility (0.2 µm)	Passes test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.