Description

Adenylyl(3'-5')Uridine Ammonium Salt is a high-purity dinucleoside monophosphate, a crucial building block in oligonucleotide synthesis and biochemical research. This compound serves as a fundamental substrate for studying RNA ligase activity, enzyme kinetics, and nucleic acid metabolism. It is essential for researchers and manufacturers in the fields of molecular biology, pharmaceutical development, and diagnostic reagent production who require reliable, well-characterized biochemical intermediates.

Application

• Oligonucleotide Synthesis: As a protected dinucleotide monomer for the chemical and enzymatic synthesis of RNA and chimeric oligonucleotides.
• Enzymology Research: A key substrate for investigating the mechanism and specificity of RNA ligases, nucleotidyltransferases, and other nucleic acid-modifying enzymes.
• Biochemical Assay Development: Used in the development of high-throughput screening assays for drug discovery targeting viral polymerases or cellular RNA repair pathways.
• Diagnostic Reagent Manufacturing: A raw material for producing specialized probes and primers used in molecular diagnostics and next-generation sequencing platforms.
• Academic & Pharmaceutical R&D: Fundamental research tool for studying non-canonical RNA structures, RNA-protein interactions, and metabolic pathways involving dinucleotides.

Basic Information

Product Name	Adenylyl(3'-5')Uridine Ammonium Salt
CAS No.	93839-87-3
Molecular Formula	C19H27N8O13P · xNH3
Molecular Weight	606.44 g/mol (free acid, anhydrous)
Synonyms	Adenylyl(3'→5')uridine ammonium salt; 3'-5' Adenylyl Uridine ammonium salt; ApU ammonium salt; Adenosine(3'-5')uridine ammonium salt; 3'-Adenylyl-uridine ammonium salt; pA-U ammonium salt; RNA Dinucleotide ApU ammonium salt; 5'-O-Phosphonoadenylyl-(3'→5')-uridine ammonium salt
EINECS	Contact for details

Quality Control

Our Adenylyl(3'-5')Uridine Ammonium Salt is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and production. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This material is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, keep under inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (HPLC)	≥ 90% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Ammonium Content	Contact for details
Solubility	Soluble in water, DMSO; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.