Description

Adenosine 5'-o-Thiomonophosphate is a chemically modified nucleotide analog where a sulfur atom replaces an oxygen atom in the phosphate group. This structural modification is critical for its role as a potent inhibitor of various enzymes, particularly in nucleotide metabolism and signaling pathways. It is an essential biochemical tool for researchers in pharmaceutical development, enzymology, and molecular biology, offering unique properties for probing enzyme mechanisms and developing therapeutic agents.

Application

• Enzyme Inhibition Studies: Used as a substrate analog to study and inhibit enzymes like adenylate kinase, 5'-nucleotidase, and other phosphotransferases.
• Biochemical Research: Serves as a key reagent in investigating nucleotide-dependent processes, signal transduction, and energy metabolism.
• Pharmaceutical R&D: Employed in the discovery and development of novel therapeutics targeting purinergic receptors and metabolic disorders.
• Diagnostic Assay Development: Acts as a component in enzymatic assays and diagnostic kits for clinical and research purposes.
• Metabolic Pathway Analysis: A tool for tracing and understanding metabolic fluxes in cellular systems.

Basic Information

Product Name	Adenosine 5'-o-Thiomonophosphate
CAS No.	93839-85-1
Molecular Formula	C10H14N5O6PS
Molecular Weight	363.29 g/mol
Synonyms	AMPS; Adenosine 5'-(Thiomonophosphate); Adenosine-5'-O-thiomonophosphate; 5'-Thioadenylic acid; 5'-Adenylic acid thioanalogue; Adenosine 5'-monothiophosphate; 5'-O-Thiomonophosphatoadenosine; Adenosine 5'-(hydrogen thiophosphate)
EINECS	Contact for details

Quality Control

Our Adenosine 5'-o-Thiomonophosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.