Description

14-Benzoyl-8-o-Methylaconine is a high-purity, semi-synthetic diterpenoid alkaloid derivative. This compound is valued for its role as a critical reference standard and advanced pharmaceutical intermediate in research and development. It is primarily utilized by professionals in the pharmaceutical, biotechnology, and phytochemical analysis sectors for method development, quality control, and novel compound synthesis.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity assessment, and quantification of related alkaloids in complex matrices via HPLC, LC-MS, and TLC.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key building block in the synthesis of novel pharmaceutical candidates targeting neurological and cardiovascular pathways.
• Biochemical Research: Employed in pharmacological studies to investigate structure-activity relationships (SAR) of diterpenoid alkaloids and their biological effects.
• Phytochemical Analysis: Acts as a critical marker compound for the quality control and standardization of plant extracts, particularly from the Aconitum genus.
• Analytical Method Development: Essential for developing and validating chromatographic and spectroscopic methods in compliance with ICH and pharmacopeial guidelines.

Basic Information

Product Name	14-Benzoyl-8-o-Methylaconine
CAS No.	93772-68-0
Molecular Formula	C32H43NO8
Molecular Weight	569.69 g/mol
Synonyms	8-O-Methyl-14-benzoylaconine; 14-Benzoyl-8-O-methylaconine; Benzoyl-8-O-methylaconine; 8-O-Methyl-14-benzoyl-aconine; Aconine, 14-benzoyl-8-O-methyl-; (1α,3α,6α,14α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13,14-tetrol 14-benzoate
EINECS	Contact for details

Quality Control

Our 14-Benzoyl-8-o-Methylaconine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity analysis, identity confirmation (IR, NMR), and residual solvent screening to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.