Description

H-Cit-Amc CAS NO 93753-78-7 is a specialized chemical building block, specifically a protected amino acid derivative. This compound is critical for advanced organic synthesis, particularly in peptide chemistry, where it enables the controlled introduction of specific functional groups. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for developing novel therapeutic agents and complex biomolecules.

Application

• Peptide Synthesis: Serves as a key intermediate in solid-phase and solution-phase peptide synthesis for constructing specific peptide sequences.
• Pharmaceutical Intermediates: Used in the research and development of active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation: Facilitates the site-specific labeling and modification of proteins, antibodies, and other biomolecules.
• Protecting Group Chemistry: Acts as a reagent where its specific protecting groups are utilized in multi-step synthetic routes.
• Chemical Biology Research: Employed in the synthesis of probes and tools for studying biological processes and enzyme mechanisms.
• Combinatorial Chemistry: Used in libraries for high-throughput screening in drug discovery programs.

Basic Information

Product Name	H-Cit-Amc
CAS No.	93753-78-7
Molecular Formula	C10H18N4O4
Molecular Weight	258.28 g/mol
Synonyms	H-Citrulline-AMC; L-Citrulline 7-amido-4-methylcoumarin; Citrulline-AMC; 7-Amino-4-methylcoumarin conjugate of L-Citrulline; AMC-labeled Citrulline; Substrate for peptidylarginine deiminase (PAD); Abz-Cit-OH; (S)-2-Amino-5-(carbamoylamino)pentanoic acid coupled to 7-amino-4-methylcoumarin
EINECS	Contact for details

Quality Control

Our H-Cit-Amc is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.