Description

(3S)-3-[[(2S)-2-[[(2S)-2-Acetamido-3-Carboxy-Propanoyl]Amino]-3-Methyl-Butanoyl]Amino]-3-[[(1S)-1-Carboxyethyl]Carbamoyl]Propanoic Acid is a high-purity, complex tripeptide derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chiral building block and intermediate for the synthesis of novel therapeutic agents, particularly in the fields of protease inhibitors and targeted drug delivery systems. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise molecular scaffolds for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex active pharmaceutical ingredients (APIs), especially protease inhibitors.
• Peptide-Based Drug Discovery: Used as a building block for constructing novel peptide and peptidomimetic drug candidates with specific biological activity.
• Bioconjugation & Linker Chemistry: Its multiple carboxylic acid groups enable its use as a linker molecule for attaching targeting moieties or payloads in antibody-drug conjugates (ADCs) and other bioconjugates.
• Biochemical Research: Employed as a substrate or inhibitor analog in enzymatic studies to investigate protease mechanisms and kinetics.
• Fine Chemical Synthesis: Serves as a high-value intermediate for custom synthesis and contract manufacturing of specialty chemicals.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(3S)-3-[[(2S)-2-[[(2S)-2-Acetamido-3-Carboxy-Propanoyl]Amino]-3-Methyl-Butanoyl]Amino]-3-[[(1S)-1-Carboxyethyl]Carbamoyl]Propanoic Acid
CAS No.	93620-52-1
Molecular Formula	C19H29N4O10
Molecular Weight	473.46 g/mol
Synonyms	N2-[(N-Acetyl-L-α-aspartyl)-L-valyl]-L-α-aspartic acid 1-(1-carboxyethyl)amide; L-α-Aspartic acid, N2-[(N-acetyl-L-α-aspartyl)-L-valyl]-, 1-(1-carboxyethyl)amide; Ac-Asp-Val-Asp(1-CEAm); Tripeptide derivative Ac-Asp-Val-Asp(CEA); N-Acetyl-Asp-Val-Asp-Carboxyethylamide; (3S)-3-(((2S)-2-((2S)-2-Acetamido-3-carboxypropanamido)-3-methylbutanamido)-3-((1S)-1-carboxyethylcarbamoyl)propanoic acid
EINECS	Contact for details

Quality Control

Our (3S)-3-[[(2S)-2-[[(2S)-2-Acetamido-3-Carboxy-Propanoyl]Amino]-3-Methyl-Butanoyl]Amino]-3-[[(1S)-1-Carboxyethyl]Carbamoyl]Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.