Description

(-)-Tropicamide is a high-purity, single-enantiomer anticholinergic agent, specifically the levorotatory isomer of tropicamide. This compound is of critical importance in pharmaceutical research and development due to its high specificity and potency as a muscarinic receptor antagonist. It is primarily required by pharmaceutical manufacturers and advanced research institutions for the development of ophthalmic solutions, neurological research tools, and as a key chiral intermediate in synthetic chemistry.

Application

• Ophthalmic Pharmaceutical Manufacturing: As the active pharmaceutical ingredient (API) in diagnostic and therapeutic eye drops for pupil dilation (mydriasis) and cycloplegia.
• Neurological Research: Used as a selective muscarinic acetylcholine receptor (mAChR) antagonist in studies of the parasympathetic nervous system and cognitive function.
• Chiral Synthesis: Serves as a valuable chiral building block or resolving agent in the asymmetric synthesis of complex bioactive molecules.
• Reference Standard: Employed as a certified reference material (CRM) in analytical laboratories for quality control, method validation, and regulatory compliance testing of ophthalmic products.
• Preclinical Studies: Utilized in animal model research to investigate ocular physiology, drug delivery, and the effects of anticholinergic agents.

Basic Information

Product Name	(-)-Tropicamide
CAS No.	92934-64-0
Molecular Formula	C17H20N2O2
Molecular Weight	284.35 g/mol
Synonyms	(-)-Tropicamide; L-Tropicamide; (S)-(-)-Tropicamide; (S)-Tropicamide; 1H-Pyrrole-3-acetic acid, α-(hydroxymethyl)-N-ethyl-N-(4-pyridinylmethyl)-, (S)-; Tropicamide S-(-)- isomer; Levotropicamide; (S)-N-Ethyl-2-phenyl-N-(pyridin-4-ylmethyl)propanamide
EINECS	Contact for details

Quality Control

Our (-)-Tropicamide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and related substances is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is kept sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.