Description

Tropicamide CAS NO 1508-75-4 is a synthetic anticholinergic agent belonging to the class of muscarinic antagonists. This compound is of critical importance in ophthalmic medicine for its potent mydriatic and cycloplegic properties, enabling detailed examination of the retina and lens. It is an essential active pharmaceutical ingredient (API) primarily required by pharmaceutical manufacturers and compounding pharmacies for the formulation of diagnostic eye drops.

Application

• Ophthalmic Diagnostic Agent: Primary use as a mydriatic to dilate the pupil for fundoscopic examinations and refractive error assessments.
• Cycloplegic Refraction: Used to temporarily paralyze the ciliary muscle, facilitating accurate measurement of refractive errors, especially in children.
• Pharmaceutical Intermediates: Serves as a key starting material or intermediate in the synthesis of more complex anticholinergic drugs.
• Research & Development: Utilized in biochemical and pharmacological research to study muscarinic acetylcholine receptor mechanisms.
• Veterinary Ophthalmology: Applied in veterinary practices for ocular examinations in animals.
• Compounding Pharmacy: Used by specialized pharmacies to prepare customized ophthalmic solutions.

Basic Information

Product Name	Tropicamide
CAS No.	1508-75-4
Molecular Formula	C17H20N2O2
Molecular Weight	284.35 g/mol
Synonyms	N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide; Tropicacyl; Mydriacyl; Bistropamide; Tropicamidum; 1H-Pyrrole-2,5-dione, 1-(2,4-dichlorophenyl)-; (RS)-N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide
EINECS	216-132-9

Quality Control

Our Tropicamide is manufactured under strict quality management systems. It is typically produced to meet pharmaceutical-grade standards, with specifications aligned with major pharmacopoeias such as USP, EP, and BP. Every batch undergoes comprehensive analytical testing including HPLC for assay and purity, identification by IR and NMR, and stringent control of related substances and residual solvents. A Certificate of Analysis (COA) is provided with each shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any individual impurity ≤ 0.5%
Water (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.