Description

Rac-Verteporfin CAS NO 130851-15-9 is a synthetic benzoporphyrin derivative and a racemic mixture of the photosensitizer Verteporfin. This compound is of significant interest in photodynamic research and pharmaceutical development due to its light-activated properties. It serves as a critical intermediate and reference standard for researchers and manufacturers in the fields of ophthalmology, oncology, and photodynamic therapy (PDT).

Application

• Primary reference standard for the analytical development and quality control of the active pharmaceutical ingredient (API) Verteporfin.
• Key intermediate in the research and synthesis of photosensitizing agents for photodynamic therapy.
• Used in preclinical studies to investigate mechanisms of action for age-related macular degeneration (AMD) treatments.
• Essential material for developing and validating analytical methods such as HPLC and LC-MS in pharmaceutical labs.
• Tool compound in biochemical research exploring light-activated cellular responses and oxidative stress pathways.
• Starting material for the preparation of specialized derivatives for targeted photodynamic applications.

Basic Information

Product Name	Rac-Verteporfin
CAS No.	130851-15-9
Molecular Formula	C41H42N4O8
Molecular Weight	718.80 g/mol
Synonyms	Racemic Verteporfin; Benzoporphyrin Derivative Monoacid Ring A (BPD-MA), Racemate; Visudyne Impurity; 9-Methyl-14-oxo-4,13,15,22-tetraoxa-3,14-diaza-1(2,6),8(1,3)-dibenzena-5(1,3),12(1,4)-dipyridinacyclodocosaphane-2,6,16,20-tetraene-10,21-dipropanoic acid, 23-(1-Methoxyethyl)-24-methyl-7,8-dihydro-; BPD-MA (racemic); CL 318952 (racemic)
EINECS	Contact for details

Quality Control

Our Rac-Verteporfin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity analysis, chiral purity assessment, and identity confirmation (IR, MS), to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at -20°C or below to minimize oxidation and ensure long-term stability. Allow the container to reach room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	Red to dark red solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Racemic mixture (approx. 1:1 ratio of enantiomers)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.