Description

Dorzolamide is a potent and selective carbonic anhydrase inhibitor, a critical active pharmaceutical ingredient (API) in ophthalmic solutions. Its primary value lies in effectively reducing intraocular pressure, making it a cornerstone in the management of ocular hypertension and open-angle glaucoma. This high-purity compound is essential for pharmaceutical manufacturers developing and producing prescription eye drops. Dorzolamide CAS NO 120279-96-1 is supplied to meet the stringent requirements of the global pharmaceutical industry.

Application

Dorzolamide is exclusively used in the pharmaceutical sector for its targeted therapeutic action. Its applications include:

• Primary Active Pharmaceutical Ingredient (API) in prescription ophthalmic solutions for glaucoma.
• Formulation of Combination Therapies, often paired with timolol for enhanced efficacy in intraocular pressure reduction.
• Manufacturing of Generic Pharmaceuticals, following patent expiry, to provide cost-effective treatment options.
• Research & Development of novel drug delivery systems for ophthalmic use.
• Clinical Trial Material for studies on new ophthalmic formulations or related therapeutic areas.

Basic Information

Product Name	Dorzolamide
CAS No.	120279-96-1
Molecular Formula	C10H16N2O4S3
Molecular Weight	324.38 g/mol
Synonyms	(4S,6S)-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide; L-671,152; MK-0507; Dorzolamide Hydrochloride; Trusopt (brand name component); Dorzolamidum; Dorzolamida
EINECS	Contact for details

Quality Control

Our Dorzolamide is manufactured under strict quality management systems. We provide material that meets or exceeds relevant pharmacopeial standards, including USP and EP monographs. Every batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via HPLC. Certificates of Analysis (COA) documenting all test results are available upon request to ensure full traceability and compliance for your regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.