Description

Homatropine CAS NO 114173-36-3 is a synthetic anticholinergic agent and a derivative of atropine, primarily valued for its mydriatic and cycloplegic properties. This compound is critical for applications requiring precise control of ocular muscles and functions. It is an essential intermediate and active ingredient for manufacturers in the pharmaceutical and fine chemical sectors, particularly those developing ophthalmic solutions and diagnostic agents.

Application

• Ophthalmic Drug Manufacturing: As a key active pharmaceutical ingredient (API) in eye drops and solutions used for pupil dilation (mydriasis) and paralysis of accommodation (cycloplegia) during eye examinations.
• Pharmaceutical Intermediates: Serves as a crucial synthetic intermediate in the production of more complex anticholinergic and spasmolytic medications.
• Research & Development: Used in biochemical and pharmacological research to study muscarinic acetylcholine receptor antagonists and their physiological effects.
• Diagnostic Agent Formulation: Employed in the formulation of diagnostic kits and agents for ophthalmic procedures in clinical settings.
• Reference Standard: Supplied as a high-purity analytical reference standard for quality control and method validation in pharmaceutical laboratories.

Basic Information

Product Name	Homatropine
CAS No.	114173-36-3
Molecular Formula	C16H21NO3
Molecular Weight	275.34 g/mol
Synonyms	Homatropine; Mandelyltropeine; Tropine mandelate; DL-Homatropine; (±)-Homatropine; Homatropinum; Homatropina; 3-[(Hydroxyphenylacetyl)oxy]-8-methyl-8-azabicyclo[3.2.1]octane
EINECS	Contact for details

Quality Control

Our Homatropine is produced and tested under a strict quality management system to ensure it meets the high standards required for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via techniques such as HPLC and IR spectroscopy. Certificates of Analysis (COA) documenting full compliance with agreed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity: ≤0.5% Total impurities: ≤1.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.