Description

3 β-Azidocholyl-2-Iodohistamine CAS NO 92921-04-5 is a specialized, high-purity synthetic intermediate designed for advanced research and development. This compound is critical for scientists working on novel molecular probes and targeted therapeutic agents due to its unique bifunctional structure. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing next-generation diagnostics and drug delivery systems.

Application

• Pharmaceutical Research: A key intermediate in the synthesis of targeted drug conjugates and radiopharmaceuticals.
• Bioconjugation Chemistry: Used for site-specific labeling of peptides, proteins, and antibodies via its reactive azide and iodohistamine groups.
• Molecular Imaging Probe Development: Serves as a precursor for creating contrast agents and tracers for diagnostic imaging techniques.
• Chemical Biology Studies: Enables the study of receptor-ligand interactions and cellular uptake mechanisms.
• Prodrug Synthesis: Employed in the design of bile acid-conjugated prodrugs to enhance bioavailability and targeting.

Basic Information

Product Name	3 β-Azidocholyl-2-Iodohistamine
CAS No.	92921-04-5
Molecular Formula	C31H45IN6O3
Molecular Weight	676.54 g/mol
Synonyms	3β-Azidocholyl-2-iodohistamine; 2-Iodohistamine 3β-azidocholate; N-[(3R)-3-Azido-24-oxocholan-24-yl]-2-(2-iodo-1H-imidazol-4-yl)ethan-1-amine; 3β-Azido-5β-cholan-24-oic acid 2-(2-iodo-1H-imidazol-4-yl)ethylamide; Azidocholyl iodohistamine; Bile acid-iodohistamine conjugate; CAS 92921-04-5
EINECS	Contact for details

Quality Control

Our 3 β-Azidocholyl-2-Iodohistamine is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry verification. A Certificate of Analysis (COA) is supplied with every batch to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and degradation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.