Description

4-(Trifluoroacetamido)Phenyl-2-Acetamido-2-Deoxy-4-o-β-Mannopyranosyl-β-Glucopyranoside is a sophisticated, high-purity carbohydrate derivative and glycosylation intermediate of significant interest in advanced pharmaceutical research and development. This compound matters for its role as a key building block in the synthesis of complex glycoconjugates and glycomimetics, enabling precise structural modifications. It is primarily needed by research institutions and pharmaceutical companies focused on developing novel therapeutics, diagnostic tools, and probes in areas such as immunology, oncology, and infectious disease.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel glycoprotein-based drugs and antibody-drug conjugates (ADCs).
• Glycobiology Research: Used as a substrate or inhibitor in enzymatic studies to investigate glycosyltransferase and glycosidase activity.
• Probe Development: Serves as a precursor for fluorescent or biotinylated carbohydrate probes used in cell surface labeling and imaging.
• Vaccine Adjuvant Research: Investigated for its potential role in modulating immune responses as part of synthetic carbohydrate antigens.
• Chemical Biology Tool: Employed in the study of carbohydrate-protein interactions relevant to cell signaling and pathogen recognition.
• Standards and Reference Material: Provides a high-purity standard for analytical method development and quality control in glycan analysis.

Basic Information

Product Name	4-(Trifluoroacetamido)Phenyl-2-Acetamido-2-Deoxy-4-o-β-Mannopyranosyl-β-Glucopyranoside
CAS No.	92689-45-7
Molecular Formula	C22H28F3N2O12
Molecular Weight	593.46 g/mol
Synonyms	4-(Trifluoroacetamido)phenyl 2-acetamido-2-deoxy-4-O-β-D-mannopyranosyl-β-D-glucopyranoside; N-{4-[(2-Acetamido-2-deoxy-4-O-β-D-mannopyranosyl-β-D-glucopyranosyl)oxy]phenyl}-2,2,2-trifluoroacetamide; TFAP-Manβ(1-4)GlcNAcβ-O-PhNH-TFA; p-Trifluoroacetamidophenyl β-D-Manp-(1→4)-β-D-GlcpNAc; Glycosylation Donor Intermediate; Chitobiose Derivative Mannosylated; 92689-45-7
EINECS	Contact for details

Quality Control

Our 4-(Trifluoroacetamido)Phenyl-2-Acetamido-2-Deoxy-4-o-β-Mannopyranosyl-β-Glucopyranoside is manufactured under strict quality systems suitable for research and development applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure consistent quality and structural integrity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This compound is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere or with desiccant to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.