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1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanol (Sodium Salt) CAS NO 92609-90-0


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CAS No.:92609-90-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanol (Sodium Salt) is a high-purity, synthetic phospholipid derivative, specifically a saturated phosphatidylethanolamine. This compound is a critical building block in advanced formulation science, valued for its role in creating stable, biocompatible lipid structures. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material sectors who require precise and reliable lipid components for complex delivery systems and membrane studies.

Application

  • Liposome and Nanoparticle Formulation: A key phospholipid component for constructing stable, uniform liposomes and lipid nanoparticles (LNPs) used in drug and gene delivery systems.
  • Biomimetic Membrane Research: Used to create model cell membranes (e.g., supported lipid bilayers) for studying membrane protein interactions, permeability, and cellular processes.
  • Diagnostic Reagent Development: Serves as a substrate or structural element in diagnostic assays and kits, particularly those involving membrane fusion or signal amplification.
  • Cosmetic and Dermal Delivery Systems: Incorporated into advanced cosmetic formulations like niosomes and transfersomes to enhance the stability and skin penetration of active ingredients.
  • Biophysical Studies: Employed in calorimetry, spectroscopy, and microscopy studies to investigate lipid bilayer properties, phase behavior, and stability.
  • Excipient for Injectable Formulations: As a component in lipid-based excipient blends for parenteral products, contributing to emulsion stability and biocompatibility.

Basic Information

Item Detail
Product Name 1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanol (Sodium Salt)
CAS No. 92609-90-0
Molecular Formula C37H73NNaO8P
Molecular Weight 713.94 g/mol
Synonyms DPPE, Sodium Salt; 1,2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamine, Sodium Salt; DPPE-Na; Phosphatidylethanolamine, 1,2-dipalmitoyl-, sodium salt; L-α-Phosphatidylethanolamine, dipalmitoyl-, sodium salt; Dipalmitoylphosphatidylethanolamine Sodium Salt; PE(16:0/16:0) Sodium Salt; (2R)-2,3-Bis(hexadecanoyloxy)propyl (2-aminoethyl) phosphate, Sodium Salt
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Quality Control

Every batch of our 1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanol (Sodium Salt) is produced and tested under strict quality management systems. We ensure compliance with relevant industry standards for high-purity biochemicals. Comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed. A detailed Certificate of Analysis (COA) documenting batch-specific results is provided with each shipment to guarantee traceability and meet your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0 %
Residual Solvents (GC) Meets ICH guidelines
Phase Transition Temperature (DSC) ~63 - 65 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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