Description

H-Lys-Amc Acoh is a specialized protected amino acid derivative, widely recognized by its CAS number 92605-76-0. This compound is a critical building block in the synthesis of complex peptides and active pharmaceutical ingredients (APIs), offering high purity and reliable reactivity. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for advanced organic synthesis and drug discovery programs.

Application

• Peptide Synthesis: A key intermediate in solid-phase and solution-phase peptide synthesis, particularly for incorporating lysine residues with protected side chains.
• Pharmaceutical Research: Serves as a crucial building block in the development and production of novel therapeutic peptides and protein-based drugs.
• Bioconjugation: Used in the preparation of peptide-protein conjugates, antibody-drug conjugates (ADCs), and other bioconjugates for targeted therapies.
• Protease Substrate Development: Employed in the design and synthesis of fluorogenic and chromogenic substrates for enzyme activity assays, particularly for proteolytic enzymes.
• Chemical Biology Probes: Acts as a precursor for creating activity-based probes to study enzyme function and mechanism in biological systems.
• Fine Chemical Intermediate: Utilized in the multistep synthesis of complex organic molecules requiring specific, protected amino acid motifs.

Basic Information

Product Name	H-Lys-Amc Acoh
CAS No.	92605-76-0
Molecular Formula	C17H25N3O4
Molecular Weight	335.40 g/mol
Synonyms	Nα-Acetyl-Nε-(7-Methoxycoumarin-4-yl)acetyl-L-lysine; Ac-Lys(AMC)-OH; L-Lysine, N2-acetyl-N6-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-; AMC-Lys(Ac)-OH; H-Lys(AMC)-Ac-OH; Ac-Lys(Amc)-OH; N-Acetyl-N'-AMC-L-lysine; 7-Methoxycoumarin-4-acetyl-L-lysine N-acetate
EINECS	Contact for details

Quality Control

Our H-Lys-Amc Acoh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure enantiomeric purity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.