Description

n-Nbd-1,2-Dilauroylphosphatidylethanolamine is a synthetic, fluorescently labeled phospholipid derivative, specifically engineered for advanced research and diagnostic applications. Its core value lies in the n-NBD (7-nitrobenz-2-oxa-1,3-diazol-4-yl) fluorophore, which provides a sensitive and stable signal for tracking lipid dynamics and membrane interactions. This compound is essential for researchers and developers in the fields of lipidomics, membrane biophysics, and the formulation of targeted drug delivery systems, such as liposomes and lipid nanoparticles.

Application

• Fluorescent Labeling in Membrane Studies: As a tracer to investigate lipid bilayer properties, membrane fluidity, fusion, and trafficking in model and cellular membranes.
• Liposome & Lipid Nanoparticle (LNP) Research: Used in the development and quality control of drug delivery vehicles to visualize encapsulation efficiency, stability, and cellular uptake.
• Biochemical Assays & Diagnostics: Serves as a critical component in assays for phospholipase activity, lipid transfer proteins, and other membrane-associated enzymes.
• Cell Biology & Imaging: Enables real-time visualization of lipid metabolism and distribution within live or fixed cells using fluorescence microscopy.
• Model System Development: Incorporation into artificial membranes and supported lipid bilayers for high-throughput screening and biosensor applications.
• Academic & Pharmaceutical R&D: A vital tool for basic research in lipid biology and for pre-clinical development of lipid-based therapeutics.

Basic Information

Product Name	n-Nbd-1,2-Dilauroylphosphatidylethanolamine
CAS No.	92558-19-5
Molecular Formula	C41H73N3O12P
Molecular Weight	831.00 g/mol
Synonyms	NBD-DLPE; 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl); N-(7-Nitro-2,1,3-benzoxadiazol-4-yl)-1,2-dilauroyl-sn-glycero-3-phosphoethanolamine; Fluorescent DLPE; NBD-PE (C12:0); NBD labeled Dipalmitoylphosphatidylethanolamine analog; NBD Fluorescent Phospholipid
EINECS	Contact for details

Quality Control

Our n-Nbd-1,2-Dilauroylphosphatidylethanolamine is produced under strict quality management protocols to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic confirmation of structure, and functional validation in assay systems. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to warm to room temperature before opening to minimize condensation and moisture uptake. For long-term stability, store under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Extinction Coefficient	~21,000 cm⁻¹M⁻¹ (in methanol, ~460 nm)
Solubility	Chloroform, Methanol, DMSO
Fluorescence Properties	Excitation ~460 nm, Emission ~534 nm (solvent dependent)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.