Description

[5-[(2-Aminoacetyl)Amino]-3,4-Dihydroxy-Oxolan-2-Yl]Methoxyphosphonic Acid is a chemically modified nucleoside analog with significant biological activity. This compound is valued for its role as a key intermediate in the synthesis of novel antiviral and anticancer agents, particularly those targeting nucleotide metabolism. It is primarily utilized by pharmaceutical R&D departments, fine chemical manufacturers, and academic research institutions engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of nucleoside-based antiviral drugs and chemotherapeutic agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to DNA/RNA synthesis and repair mechanisms.
• Prodrug Development: Serves as a precursor for prodrugs designed to improve bioavailability and targeted delivery of active pharmaceutical ingredients (APIs).
• Antiviral Agent Synthesis: Key intermediate in the production of experimental compounds targeting viral polymerases.
• Labeled Compound Synthesis: Used in the preparation of isotopically labeled (e.g., C13, N15) analogs for metabolic pathway tracing and pharmacokinetic studies.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of nucleotide analogs.

Basic Information

Item	Detail
Product Name	[5-[(2-Aminoacetyl)Amino]-3,4-Dihydroxy-Oxolan-2-Yl]Methoxyphosphonic Acid
CAS No.	92379-77-6
Molecular Formula	C7H13N2O8P
Molecular Weight	284.16 g/mol
Synonyms	5'-O-[(N-Glycyl)amino]-5'-deoxyadenosine 5'-(dihydrogen phosphate); Glycylphosphoadenosine; 5'-Deoxy-5'-(glycylamino)adenosine 5'-phosphate; Adenosine-5'-[N-(glycyl)phosphoramidate]; 5'-O-[N-(Aminoacetyl)]-5'-deoxyadenosine 5'-phosphate; 5'-Glycylphosphamidate Adenosine Derivative
EINECS	Contact for details

Quality Control

Our production of [5-[(2-Aminoacetyl)Amino]-3,4-Dihydroxy-Oxolan-2-Yl]Methoxyphosphonic Acid adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch is analyzed to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific test results are provided and can be tailored to meet customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.