Description

6-(Glutathion-S-Yl)-4-Bromocatechol is a specialized biochemical reference standard and research compound. This molecule is significant as a key metabolite and biomarker in toxicological studies, particularly for investigating the metabolic pathways and detoxification mechanisms of brominated aromatic compounds. It is primarily needed by researchers and quality control laboratories in the pharmaceutical, environmental science, and chemical safety assessment sectors for analytical method development and metabolic profiling.

Application

• Biochemical Research: Used as a high-purity reference standard in studies of glutathione conjugation (Phase II metabolism) and the bioactivation pathways of brominated phenols.
• Toxicology & Metabolite Identification: Serves as a critical analytical standard for the identification and quantification of specific mercapturic acid pathway metabolites in in vitro and in vivo studies.
• Analytical Method Development: Employed for calibrating instruments and validating analytical methods (e.g., LC-MS/MS, HPLC) in forensic and environmental toxicology laboratories.
• Pharmaceutical Impurity Profiling: Acts as a marker compound in stability studies and impurity characterization for drug substances and products derived from or containing brominated catechol intermediates.
• Environmental Monitoring: Utilized in research to trace the metabolic fate and human exposure biomarkers of brominated environmental contaminants.

Basic Information

Product Name	6-(Glutathion-S-Yl)-4-Bromocatechol
CAS No.	92263-88-2
Molecular Formula	C₁₆H₂₁BrN₃O₈S
Molecular Weight	495.33 g/mol
Synonyms	4-Bromo-6-(glutathion-S-yl)catechol; 4-Bromo-6-S-glutathionylcatechol; 6-(GS-yl)-4-Bromocatechol; Glutathione conjugate of 4-bromocatechol; 2-Bromo-5-(glutathion-S-yl)hydroquinone (tautomer); Bromocatechol Glutathione Adduct; NSC 339586
EINECS	Contact for details

Quality Control

Every batch of 6-(Glutathion-S-Yl)-4-Bromocatechol is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results from advanced analytical techniques are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light tan solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area Percent)
Water Content (KF)	≤ 2.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.