Description

Toripristone CAS NO 91935-26-1 is a synthetic steroid compound known for its potent antiprogestogenic activity. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the study of hormone-responsive systems. It is primarily utilized by research institutions and pharmaceutical companies engaged in developing novel therapeutic agents for endocrinology and oncology.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced steroid-based drug candidates.
• Biomedical Research: Used as a reference standard and active agent in preclinical studies investigating progesterone receptor (PR) antagonism.
• Endocrinology Studies: Employed in laboratory research to understand hormone regulation and develop treatments for hormone-dependent conditions.
• API Development: Acts as a precursor in the development and scale-up of Active Pharmaceutical Ingredients (APIs) targeting reproductive health.

Basic Information

Product Name	Toripristone
CAS No.	91935-26-1
Molecular Formula	C29H35NO4
Molecular Weight	461.60 g/mol
Synonyms	Toripristone; 91935-26-1; ZK 98.299; ZK-98299; 11β-[4-(Dimethylamino)phenyl]-17β-hydroxy-17α-(3-hydroxypropyl)-13α-methyl-4,9-gonadien-3-one; 11β-[4-(Dimethylamino)phenyl]-17β-hydroxy-17α-(3-hydroxypropyl)-13α-methyl-4,9-gonadien-3-one
EINECS	Contact for details

Quality Control

Our Toripristone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research-grade materials. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.