Description

Biotinyl-6-Aminoquinoline CAS NO 91853-89-3 is a high-purity biochemical reagent that combines the vitamin biotin with a fluorescent quinoline moiety. This compound is valued for its strong and specific binding to avidin and streptavidin, coupled with its inherent fluorescent properties, enabling sensitive detection and labeling applications. It is an essential tool for researchers and manufacturers in the life sciences, diagnostics, and pharmaceutical development sectors.

Application

• Fluorescent Labeling & Probes: Used to create fluorescently tagged biomolecules (e.g., antibodies, nucleic acids) for detection in assays like ELISA, Western blotting, and immunohistochemistry.
• Diagnostic Assay Development: Serves as a key component in the development of sensitive diagnostic kits for disease markers, leveraging the biotin-streptavidin amplification system.
• Cell Imaging & Microscopy: Employed for fluorescent labeling of cell surface receptors or intracellular targets to visualize biological processes.
• Affinity Chromatography: Can be immobilized to create resins for the purification of avidin/streptavidin-tagged proteins or other biotinylated molecules.
• Drug Discovery & Target Identification: Utilized in high-throughput screening (HTS) and pull-down assays to identify and characterize molecular interactions.
• Biosensor Fabrication: Incorporated into sensor surfaces for the detection of specific analytes with high sensitivity due to the fluorescent signal.

Basic Information

Product Name	Biotinyl-6-Aminoquinoline
CAS No.	91853-89-3
Molecular Formula	C₂₀H₂₄N₄O₂S
Molecular Weight	384.50 g/mol
Synonyms	6-((Biotinoyl)amino)quinoline; Biotin-6-aminoquinoline; N-(6-Quinolinyl)biotinamide; Biotinamidoquinoline; Quinoline-6-biotinamide; Biotinylated 6-aminoquinoline; 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-(quinolin-6-yl)pentanamide
EINECS	Contact for details

Quality Control

Our Biotinyl-6-Aminoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.