Description

1-(n-6-Amino-n-Hexyl)Carbamoylimidazole is a specialized bifunctional reagent featuring both a reactive imidazole carbamate group and a primary amine. This compound matters as a versatile building block for the synthesis of amide bonds and the preparation of affinity chromatography media, drug conjugates, and modified biomolecules. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for developing targeted therapies, diagnostic agents, and advanced separation systems.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, particularly for creating amide-linked conjugates.
• Bioconjugation & Labeling: Used to covalently attach drugs, dyes, or other molecules to proteins, antibodies, peptides, and oligonucleotides via its amine-reactive carbamoylimidazole group.
• Affinity Chromatography Ligand Synthesis: Serves as a spacer arm for immobilizing ligands (e.g., enzymes, inhibitors) onto solid supports like agarose or sepharose beads for purification.
• Polymer & Material Science: Functional monomer for creating specialty polymers, hydrogels, or surface coatings with reactive amine handles.
• Crosslinking Agent: Facilitates the crosslinking of molecules containing carboxyl or amine groups in biochemical and material applications.
• Research & Development: Valuable tool compound in chemical biology and medicinal chemistry research for exploring new synthetic pathways and bioconjugation strategies.

Basic Information

Product Name	1-(n-6-Amino-n-Hexyl)Carbamoylimidazole
CAS No.	91853-59-7
Molecular Formula	C10H18N4O
Molecular Weight	210.28 g/mol
Synonyms	1-[(6-Aminohexyl)carbamoyl]imidazole; N-(6-Aminohexyl)imidazole-1-carboxamide; 1H-Imidazole-1-carboxamide, N-(6-aminohexyl)-; 6-Aminohexyl imidazolylcarbamate; AHC-Imidazole; Carbonyldiimidazole hexanediamine derivative; 1-Carbamoylimidazole, 6-aminohexyl-; N6-(Imidazole-1-carbonyl)hexane-1,6-diamine
EINECS	Contact for details

Quality Control

Our 1-(n-6-Amino-n-Hexyl)Carbamoylimidazole is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Store away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.