Description

1-o-Hexadecyl-2-n-Methylcarbamyl-Sn-Glycero-3-Phosphocholine is a synthetic, high-purity phospholipid derivative, specifically a lysophosphatidylcholine analog, designed for advanced research and development applications. This compound is valued for its role as a key intermediate and functional component in the formulation of lipid-based delivery systems and biomimetic membranes. It is primarily utilized by researchers and product developers in the pharmaceutical, biotechnology, and advanced materials sectors, particularly for drug delivery, cell membrane studies, and the creation of specialized liposomal formulations.

Application

• Liposomal Drug Delivery Systems: As a structural and functional component in the formulation of liposomes and other lipid nanoparticles for targeted drug delivery.
• Biomembrane Research: Used in model membrane systems (e.g., vesicles, supported lipid bilayers) to study membrane fluidity, protein-lipid interactions, and signaling pathways.
• Pharmaceutical Intermediates: Serves as a critical synthetic intermediate for the production of more complex phospholipid-based active pharmaceutical ingredients (APIs) and excipients.
• Cell Culture & Transfection Reagents: A component in specialized transfection reagents and cell culture supplements to enhance membrane permeability and cellular uptake.
• Cosmetic & Dermal Formulations: Incorporated into advanced cosmetic products for its emulsifying properties and potential to improve skin barrier function and active ingredient penetration.
• Diagnostic Assay Development: Used in the development of diagnostic kits and biosensors that rely on lipid membrane platforms for analyte detection.

Basic Information

Product Name	1-o-Hexadecyl-2-n-Methylcarbamyl-Sn-Glycero-3-Phosphocholine
CAS No.	91575-58-5
Molecular Formula	C26H55N2O7P
Molecular Weight	538.70 g/mol
Synonyms	1-Hexadecyl-2-(methylcarbamoyl)-sn-glycero-3-phosphocholine; 2-(Methylcarbamoyl)-1-hexadecyl-sn-glycero-3-phosphocholine; Lyso-PAF Methylcarbamate; C16-LysoPC Methylcarbamate; 1-O-Hexadecyl-2-(N-methylcarbamoyl)-sn-glycero-3-phosphocholine; Methylcarbamyl Lyso Platelet-Activating Factor Analog; Phospholipid Derivative 91575-58-5
EINECS	Contact for details

Quality Control

Our 1-o-Hexadecyl-2-n-Methylcarbamyl-Sn-Glycero-3-Phosphocholine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We can support development projects requiring compliance with cGMP guidelines for non-clinical and early-phase clinical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. Due to its hygroscopic nature, the container should be allowed to equilibrate to room temperature before opening to minimize moisture ingress. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (by NMR)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.