Description

1H-Pyrrole-2,5-Dione,1-[4-[2-[(2,5-Dioxo-1-Pyrrolidinyl)Oxy]-2-Oxoethyl]Phenyl]- is a specialized heterocyclic compound featuring a maleimide core linked to a phenyl ring via an ester-containing spacer. This molecular architecture makes it a valuable high-purity intermediate for advanced material synthesis, particularly in applications requiring precise chemical conjugation. It is primarily sought by R&D and production teams in the pharmaceutical, polymer, and specialty chemical industries for developing novel drug conjugates, functional polymers, and cross-linking agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutics via maleimide-thiol chemistry.
• Polymer Science: Used as a functional monomer or cross-linker in the production of advanced polymers, hydrogels, and coatings with tailored properties.
• Bioconjugation: Essential reagent for labeling proteins, peptides, and other biomolecules for diagnostic assays and research applications.
• Material Functionalization: Imparts reactive sites onto surfaces, nanoparticles, and nanomaterials for further chemical modification.
• Research & Development: Serves as a critical reagent in organic synthesis and medicinal chemistry research for exploring new chemical entities.

Basic Information

Product Name	1H-Pyrrole-2,5-Dione,1-[4-[2-[(2,5-Dioxo-1-Pyrrolidinyl)Oxy]-2-Oxoethyl]Phenyl]-
CAS No.	91574-33-3
Molecular Formula	C16H14N2O6
Molecular Weight	330.29 g/mol
Synonyms	1-[4-[2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]phenyl]-1H-pyrrole-2,5-dione; 4-(2-Maleimidoethoxy)benzyl Maleimide; N-(4-(2-Maleimidoethoxy)benzyl)maleimide; Maleimide-PEG1-Benzyl-Maleimide; BM(PEG)1; BM(PEG)2 (Note: Verify specific linker length); Bifunctional Maleimide Crosslinker; 1-[4-(2-Maleimidylethoxy)phenyl]-1H-pyrrole-2,5-dione
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.