Description

1-Palmitoyl-2-Linoleoyl-Sn-Glycero-3-[Phospho-L-Serine] (Sodium Salt) is a high-purity, synthetic phospholipid, specifically a phosphatidylserine (PS) species with defined fatty acid chains. This compound is critical for research and development in advanced life sciences, serving as a key building block for creating biomimetic membranes and delivery systems. It is essential for pharmaceutical researchers, formulation scientists, and diagnostic developers working on liposomal drug delivery, cell signaling studies, and neurological research applications.

Application

• Liposomal Drug Delivery Systems: A key excipient for formulating stable, target-specific liposomes to enhance the bioavailability and efficacy of therapeutic agents.
• Biomembrane & Cell Biology Research: Used to create model membranes (e.g., vesicles, supported lipid bilayers) for studying membrane protein interactions, fusion processes, and cellular signaling pathways.
• Neurological & Cognitive Health Research: As a specific phosphatidylserine species, it is utilized in studies investigating neuronal membrane integrity, synaptic function, and potential nutraceutical applications.
• Diagnostic Reagent Formulation: Incorporated into assay kits and diagnostic reagents that require specific lipid environments for optimal performance.
• Cosmetic & Dermal Formulations: Employed in high-end cosmetic products for its skin-barrier repair and moisturizing properties in advanced nano-emulsions.
• Biophysical Studies: Essential for techniques like surface plasmon resonance (SPR) and fluorescence spectroscopy to investigate lipid-protein and lipid-lipid interactions.

Basic Information

Item	Details
Product Name	1-Palmitoyl-2-Linoleoyl-Sn-Glycero-3-[Phospho-L-Serine] (Sodium Salt)
CAS No.	91178-24-4
Molecular Formula	C42H75NNaO10P
Molecular Weight	807.99 g/mol
Synonyms	PS(16:0/18:2); 1-Palmitoyl-2-linoleoyl-phosphatidylserine (sodium salt); L-α-Phosphatidylserine (16:0/18:2(9Z,12Z)); Sodium 1-palmitoyl-2-[(9Z,12Z)-octadeca-9,12-dienoyl]-sn-glycero-3-phospho-L-serine; Phosphatidylserine (Palmitoyl, Linoleoyl); PLPS; (16:0-18:2) PS; 1,2-Diacyl-sn-glycero-3-phospho-L-serine (sodium salt) with specified acyl chains.
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Linoleoyl-Sn-Glycero-3-[Phospho-L-Serine] (Sodium Salt) is manufactured under strict quality systems suitable for research and pharmaceutical development. Each batch is characterized using advanced analytical techniques to ensure identity, purity, and consistency. Comprehensive Certificates of Analysis (COA) are provided, detailing results for assay, fatty acid profile, and critical impurities. Production adheres to cGMP guidelines where applicable, ensuring traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR & MS)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Fatty Acid Composition (GC)	Palmitic acid (16:0): 45-55%; Linoleic acid (18:2): 45-55%
Water Content (KF)	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Microbial Limits	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.