Description

1,2-Bis(Decanoylthio)-1,2-Dideoxyglycerol-3-Phosphorylethanolamine CAS NO 90906-06-2 is a specialized synthetic phospholipid derivative, serving as a critical building block in advanced lipid-based formulations. Its unique structure, featuring decanoylthio groups, makes it a valuable precursor for creating functionalized liposomes and lipid nanoparticles with tailored surface properties. This compound is essential for researchers and formulators in the pharmaceutical and biotechnology industries, particularly for developing targeted drug delivery systems, diagnostic agents, and novel biomaterials.

Application

• Lipid Nanoparticle (LNP) Formulation: A key functional component in the synthesis of next-generation LNPs for mRNA, siRNA, and other nucleic acid delivery platforms.
• Functionalized Liposome Production: Used to engineer liposomes with specific surface characteristics for enhanced targeting, stability, and cellular uptake in drug delivery.
• Biomimetic Membrane Research: Serves as a model compound in biophysical studies to understand membrane dynamics, protein-lipid interactions, and signal transduction.
• Diagnostic Agent Development: Incorporated into contrast agents or probes for medical imaging techniques such as MRI or fluorescence imaging.
• Gene Therapy Vector Design: A critical raw material for non-viral vector development, improving the efficiency and specificity of genetic material transfer.
• Cosmetic & Dermal Delivery Systems: Employed in high-end cosmetic formulations to create nano-carriers for the controlled release of active ingredients.

Basic Information

Product Name	1,2-Bis(Decanoylthio)-1,2-Dideoxyglycerol-3-Phosphorylethanolamine
CAS No.	90906-06-2
Molecular Formula	C27H52NO7PS2
Molecular Weight	581.80 g/mol
Synonyms	1,2-Didecanoylthio-sn-glycero-3-phosphoethanolamine; Decanoylthio Phosphatidylethanolamine Analog; 1,2-Bis(decanoylthio)-sn-glycero-3-phosphoethanolamine; Thioester PE Lipid; C10-Thio PE; DTPE; Phospholipid derivative with decanoyl thioester; Lipid anchor precursor
EINECS	Contact for details

Quality Control

Our 1,2-Bis(Decanoylthio)-1,2-Dideoxyglycerol-3-Phosphorylethanolamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical and research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use. For long-term storage, desiccants are recommended.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.