Description

4,4-Difluororetinyl Acetate is a specialized fluorinated derivative of vitamin A, designed for advanced research and synthesis applications. This high-purity intermediate is critical for developing novel compounds in medicinal chemistry and life sciences, where precise molecular modification is required. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on retinoid-based therapeutics, metabolic studies, and probe molecule development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel fluorinated retinoid analogs for drug discovery programs.
• Biochemical Research: Used as a probe or substrate in enzymatic studies related to vitamin A metabolism and signaling pathways.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies by introducing fluorine atoms to modulate the properties of retinoid molecules.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, value-added molecules for academic and industrial research.

Basic Information

Product Name	4,4-Difluororetinyl Acetate
CAS No.	90660-22-3
Molecular Formula	C22H30F2O2
Molecular Weight	364.48 g/mol
Synonyms	Retinyl Acetate, 4,4-Difluoro-; 4,4-Difluoro Retinyl Acetate; 4,4-Difluoro Vitamin A Acetate; (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-4,4-difluoro-2,4,6,8-nonatetraen-1-ol Acetate; 4,4-Difluoro Retinol Acetate; 4,4-Difluoroall-trans-Retinyl Acetate; 4,4-Difluoro Retinyl Acetate (all-trans)
EINECS	Contact for details

Quality Control

Our 4,4-Difluororetinyl Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for research chemicals, ensuring material integrity for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.