Description

14-Benzoyloxyyohimbine is a semi-synthetic derivative of the natural alkaloid yohimbine, characterized by the introduction of a benzoyloxy group. This structural modification is significant as it can alter the compound's pharmacological profile, bioavailability, and selectivity, making it a valuable intermediate for advanced pharmaceutical research and development. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly those targeting neurological and cardiovascular systems.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of new drug candidates, especially those derived from yohimbine alkaloids.
• Biochemical Research: Used as a reference standard or probe in studies investigating adrenergic receptor interactions and signal transduction pathways.
• Preclinical Development: Serves as a starting material for creating analogs with optimized potency, selectivity, or metabolic stability for therapeutic applications.
• Academic Research: Utilized in university and institutional labs for chemical and pharmacological studies on alkaloid derivatives.

Basic Information

Product Name	14-Benzoyloxyyohimbine
CAS No.	90362-87-1
Molecular Formula	C27H30N2O4
Molecular Weight	446.54 g/mol
Synonyms	14-Benzoyloxy-17α-hydroxyyohimban-16α-carboxylic acid methyl ester; 14-Benzoyloxy-17α-hydroxyyohimban-16α-carboxylic acid methyl ester; 14-Benzoyloxyyohimbine; Yohimbine 14-benzoate; 14-O-Benzoylyohimbine
EINECS	Contact for details

Quality Control

Our 14-Benzoyloxyyohimbine is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.