Description

α-n-Benzyloxycarbonyl-Phenylalanyl-Arginyl-4-Methoxy-β-Naphthylamide is a specialized synthetic peptide derivative used as a critical substrate and biochemical tool. This compound matters for its role in enzymology, particularly in the study and detection of proteolytic enzyme activity. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and diagnostic kit manufacturers for developing sensitive assays and studying enzyme kinetics and inhibition.

Application

• Protease/Peptidase Substrate: A key chromogenic or fluorogenic substrate for the detection and quantification of specific proteolytic enzymes like trypsin, thrombin, and other serine proteases.
• Biochemical Research: Used in enzymatic assays to study enzyme kinetics, mechanism of action, and for the screening of potential protease inhibitors in drug discovery.
• Diagnostic Development: Employed in the formulation of diagnostic kits and reagents for clinical and research purposes to measure protease activity in biological samples.
• Pharmaceutical R&D: Serves as an intermediate or tool compound in the development of therapeutic agents targeting proteolytic pathways.
• Quality Control in Biotechnology: Used as a standard or reference material to calibrate assays and ensure the consistency of enzyme-based bioprocesses.

Basic Information

Product Name	α-n-Benzyloxycarbonyl-Phenylalanyl-Arginyl-4-Methoxy-β-Naphthylamide
CAS No.	90332-96-0
Molecular Formula	C39H48N8O7
Molecular Weight	740.85 g/mol
Synonyms	Z-Phe-Arg-4MβNA; Benzyloxycarbonyl-Phenylalanyl-Arginyl-4-Methoxy-2-Naphthylamide; CBZ-Phe-Arg-4-Methoxy-β-Naphthylamide; Substrate for Trypsin-like Proteases; Chromogenic Substrate 90332-96-0; Protease Substrate Z-F-R-4MβNA; Nα-Benzyloxycarbonyl-L-phenylalanyl-L-arginyl-4-methoxy-2-naphthylamide
EINECS	Contact for details

Quality Control

Our α-n-Benzyloxycarbonyl-Phenylalanyl-Arginyl-4-Methoxy-β-Naphthylamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and diagnostic applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on dried basis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.