Description

Carboxypeptidase P is a proteolytic enzyme that specifically cleaves C-terminal proline residues from peptides and proteins. This unique specificity makes it an indispensable tool for protein sequencing, peptide mapping, and structural analysis in advanced biochemical research. It is critical for laboratories and industries requiring precise enzymatic digestion for proteomics, biopharmaceutical development, and quality control of peptide-based products.

Application

• Protein Sequencing & Structural Analysis: Essential for determining the C-terminal amino acid sequence of proteins and peptides, particularly those ending in proline.
• Peptide Mapping: Used in conjunction with other proteases to generate overlapping peptide fragments for comprehensive protein characterization.
• Biopharmaceutical Development: Employed in the analysis and quality control of therapeutic peptides and proteins, including monoclonal antibodies.
• Proteomics Research: A key reagent in bottom-up proteomics workflows for sample preparation prior to mass spectrometry analysis.
• Enzyme & Substrate Specificity Studies: Utilized to study enzyme mechanisms and substrate specificity due to its unique proline-cleaving activity.
• Food Science & Biochemistry: Applied in research to analyze protein hydrolysates and understand protein functionality in complex matrices.

Basic Information

Product Name	Carboxypeptidase P
CAS No.	9075-64-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Carboxypeptidase P (Aspergillus); Proline-specific Carboxypeptidase; Carboxypeptidase Y (related); CP-P; Proline Carboxypeptidase; Aspergillopepsin II (precursor); Acid Carboxypeptidase; EC 3.4.16.-
EINECS	Contact for details

Quality Control

Our Carboxypeptidase P is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and high enzymatic activity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as specific activity, purity, and stability. We support research and industrial applications requiring reliable and well-characterized enzymatic reagents.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and activity. For long-term storage, desiccants are recommended.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (IR)	Conforms
Specific Activity	> 50 units/mg protein
Protein Content (Biuret)	> 90%
Solubility	Soluble in water or buffer
Loss on Drying	< 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.