Description

6-Phosphogluconic Dehydrogenase is a critical oxidoreductase enzyme that catalyzes the decarboxylation of 6-phosphogluconate to ribulose 5-phosphate in the pentose phosphate pathway. This enzymatic activity is essential for cellular metabolism, linking carbohydrate catabolism to the generation of NADPH and pentose sugars for biosynthesis. It is a vital reagent for researchers and manufacturers in biochemical research, diagnostic kit production, and pharmaceutical development, where precise enzymatic activity is required.

Application

• Biochemical Research & Assay Development: A key component in enzymatic assays to study the pentose phosphate pathway, metabolic flux, and cellular redox states.
• Diagnostic Manufacturing: Used as a critical reagent in the formulation of clinical diagnostic kits for measuring glucose-6-phosphate dehydrogenase (G6PD) activity and related metabolic disorders.
• Pharmaceutical & Biotechnology: Employed in enzyme-coupled reactions for the synthesis of fine chemicals, intermediates, and in metabolic engineering applications.
• Food & Beverage Analysis: Utilized in enzymatic methods for the specific detection and quantification of sugars and related metabolites in quality control laboratories.
• Academic & Industrial Enzymology: Serves as a standard enzyme for kinetic studies, inhibitor screening, and educational purposes in biochemistry.

Basic Information

Product Name	6-Phosphogluconic Dehydrogenase
CAS No.	9073-95-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	6-Phosphogluconate Dehydrogenase; Phosphogluconate Dehydrogenase; 6PGDH; PGD; EC 1.1.1.44; 6-Phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating); Oxidative Pentose Phosphate Pathway Enzyme
EINECS	Contact for details

Quality Control

Our 6-Phosphogluconic Dehydrogenase is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and high specific activity. Each lot is characterized for purity and enzymatic performance. Certificates of Analysis (COA) detailing specific activity, purity, and stability are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at 2-8°C. Avoid repeated freeze-thaw cycles. Keep the product under the recommended conditions to maintain optimal enzymatic activity.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Conforms
Specific Activity	≥ [Value] units/mg protein
Purity (SDS-PAGE)	≥ 90%
Protein Content (Biuret)	Contact for details
Stabilizers / Buffers	Present (as specified per grade)
Solubility	Completely soluble in appropriate buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.