Description

Diethylaminoethyl Dextran Hydrochloride is a cationic polysaccharide derivative widely used as a transfection reagent and a versatile polymeric carrier in life sciences. Its value lies in its ability to form complexes with nucleic acids, facilitating their efficient delivery into cells for research and development applications. This product is essential for biotechnology and pharmaceutical companies engaged in gene therapy research, vaccine development, and advanced cell culture processes.

Application

• Nucleic Acid Transfection: A key reagent for the delivery of DNA, RNA, and oligonucleotides into mammalian cells in vitro.
• Gene Therapy Research: Used as a non-viral vector in preclinical studies for gene delivery and expression.
• Vaccine Development: Serves as an adjuvant or delivery system to enhance immune responses in experimental formulations.
• Protein Purification: Acts as a cationic exchanger in chromatography for the separation and purification of biomolecules.
• Cell Culture & Tissue Engineering: Utilized as a substrate or scaffold modifier to influence cell adhesion and growth.
• Diagnostic Assays: Employed in the development of diagnostic kits and biosensors as a coating or complexing agent.

Basic Information

Product Name	Diethylaminoethyl Dextran Hydrochloride
CAS No.	9064-91-9
Molecular Formula	(C6H10O5)n·(C6H14NO)m·HCl
Molecular Weight	Variable (Polymer)
Synonyms	DEAE-Dextran hydrochloride; Diethylaminoethyl-Dextran HCl; DEAE-Dextran; 2-(Diethylamino)ethyl dextran hydrochloride; Dextran 2-(diethylamino)ethyl ether hydrochloride; Poly[1→6)-α-D-glucopyranosyl-(1→3)-α-D-glucopyranosyl-(1→] 2-(diethylamino)ethyl ether hydrochloride; Cationic Dextran; DEAE-D
EINECS	Contact for details

Quality Control

Our Diethylaminoethyl Dextran Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure consistency, purity, and performance for critical research applications. Certificates of Analysis (COA) detailing specifications such as nitrogen content, substitution degree, molecular weight distribution, and bioburden are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a desiccated environment to prevent moisture absorption and maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms
Assay (Nitrogen Content)	3.0 - 4.0 % (or as per grade)
Degree of Substitution	0.3 - 0.6 (or as per grade)
Molecular Weight	Specified range (e.g., 500,000 Da) available
pH (in solution)	4.0 - 7.0
Loss on Drying	≤ 5.0 %
Residue on Ignition	≤ 1.0 %
Bioburden	To meet research-grade requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.