Description

β-1,4-Galactosyl Transferase I Human, Recombinant is a highly purified enzyme crucial for the biosynthesis of glycoproteins and glycolipids. This recombinant human form offers superior consistency and activity for research and bioprocessing applications where precise glycosylation is required. It is an essential tool for biopharmaceutical development, glycobiology research, and the synthesis of complex carbohydrates.

Application

• Glycoprotein Engineering: Used in the in vitro synthesis and remodeling of therapeutic glycoproteins to optimize their pharmacokinetic properties and efficacy.
• Glycan Array Production: A key reagent for enzymatic synthesis of defined glycan structures on arrays for high-throughput binding studies and diagnostic development.
• Biopharmaceutical R&D: Critical for studying and controlling glycosylation patterns of monoclonal antibodies, hormones, and other recombinant protein drugs.
• Enzymatic Synthesis: Catalyzes the transfer of galactose from UDP-galactose to N-acetylglucosamine residues in the production of specific oligosaccharides and glycoconjugates.
• Diagnostic Reagent Manufacturing: Employed in the production of standardized reagents for clinical assays that detect specific antibodies or lectins based on glycan recognition.
• Cell Biology Research: Used to probe the role of specific glycan structures in cell signaling, adhesion, and immune response mechanisms.

Basic Information

Product Name	β-1,4-Galactosyl Transferase I Human, Recombinant
CAS No.	9054-94-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	β-1,4-Galactosyltransferase I; B4GALT1; Lactose Synthase A Protein; UDP-Galactose:β-D-Glucosaminylglycopeptide β-1,4-Galactosyltransferase; N-Acetyllactosamine Synthase; Glycoprotein 4-β-Galactosyltransferase; EC 2.4.1.38; Recombinant Human β4Gal-T1
EINECS	Contact for details

Quality Control

Our recombinant enzyme is produced under stringent conditions to ensure high purity, specific activity, and lot-to-lot consistency. Each batch is subjected to a comprehensive battery of tests including SDS-PAGE, activity assays, and endotoxin level verification. Certificates of Analysis (COA) detailing purity, activity (U/mg), and bioburden are provided to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation. Aliquot reconstituted enzyme to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solution
Purity (SDS-PAGE)	> 95%
Specific Activity	> XX U/mg (Contact for details)
Protein Content (Bradford)	XX mg/vial (Contact for details)
Endotoxin Level (LAL)	< 1.0 EU/μg
Identification (Activity)	Conforms
Bioburden	Meets specification

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.