Description

L-Transaminase, Branched-Chain is a specialized enzyme that catalyzes the reversible transfer of an amino group between branched-chain amino acids (leucine, isoleucine, valine) and α-ketoglutarate. This biocatalyst is critical for the biosynthesis and metabolic regulation of essential amino acids, offering high stereoselectivity and efficiency under mild reaction conditions. It is a vital tool for pharmaceutical manufacturers, research institutions, and fine chemical producers engaged in the synthesis of chiral amines, active pharmaceutical ingredients (APIs), and metabolic pathway studies.

Application

• Chiral Amine Synthesis: Key biocatalyst for the asymmetric synthesis of enantiomerically pure amines, crucial for pharmaceutical intermediates.
• Active Pharmaceutical Ingredient (API) Manufacturing: Used in enzymatic cascades for the production of complex drug molecules, including treatments for metabolic disorders.
• Diagnostic Reagent Production: Component in clinical diagnostic kits for measuring branched-chain amino acid levels in blood plasma.
• Biocatalysis & Process Development: Enables greener, more sustainable chemical processes in fine chemical and agrochemical synthesis.
• Metabolic Pathway Research: Essential tool for in vitro studies of amino acid metabolism, enzyme kinetics, and disease mechanisms.
• Food & Feed Additive Development: Investigated for applications in enhancing the nutritional profile of specialty food and animal feed products.

Basic Information

Product Name	L-Transaminase, Branched-Chain
CAS No.	9054-68-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Branched-Chain Amino Acid Transaminase; BCAT; Leucine Transaminase; L-Amino Acid Transaminase; 2-Oxoglutarate Aminotransferase; EC 2.6.1.42; Transaminase B; Branched-Chain Aminotransferase
EINECS	Contact for details

Quality Control

Our L-Transaminase, Branched-Chain is produced and tested under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure activity, purity, and consistency. Certificates of Analysis (COA) detailing specific activity (U/mg), protein content, and purity are provided with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical-grade enzymes, ensuring reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent moisture uptake, which can affect enzymatic activity. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Specific Activity	≥ [Value] U/mg protein
Protein Content (Biuret)	≥ [Value] %
Purity (SDS-PAGE)	≥ [Value] %
pH (in solution)	7.0 - 7.5
Solubility	Clear solution in specified buffer
Identification (Activity)	Conforms
Endotoxin (LAL)	< [Value] EU/mg (for specific grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.