Description

Chondro-4-Sulfatase From Proteus Vulgaris is a highly specific enzyme that catalyzes the hydrolysis of the 4-sulfate ester groups from chondroitin sulfate A and C. This enzymatic activity is critical for the structural analysis and controlled degradation of glycosaminoglycans (GAGs). It is an essential reagent for researchers and manufacturers in the biochemical, pharmaceutical, and diagnostic industries, particularly for studying connective tissue metabolism and developing therapeutic agents.

Application

• Biochemical Research: Used for the specific desulfation of chondroitin 4-sulfate to study GAG structure, function, and metabolism.
• Pharmaceutical Development: Employed in the production and analysis of low molecular weight heparins and other glycosaminoglycan-based therapeutics.
• Diagnostic Reagent Manufacturing: A key component in enzymatic assay kits for the detection and quantification of specific GAGs in biological samples.
• Glycobiology Studies: Essential for sequencing complex carbohydrates and understanding sulfation patterns in proteoglycans.
• Quality Control: Used in biopharmaceutical labs to analyze and characterize raw materials and finished products containing sulfated polysaccharides.
• Enzyme Characterization: Serves as a standard or reference material for studying sulfatase enzyme kinetics and mechanisms.

Basic Information

Product Name	Chondro-4-Sulfatase From Proteus Vulgaris
CAS No.	9045-75-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Chondroitinase ABC (EC 4.2.2.4); Chondroitin ABC lyase; Chondroitin sulfate ABC lyase; Chondroitin sulfate eliminase; Chondroitin ABC eliminase; Proteus vulgaris chondroitin sulfate lyase; Chondroitin sulfate hydrolase
EINECS	Contact for details

Quality Control

Our Chondro-4-Sulfatase is produced and tested under stringent quality management systems. Each lot undergoes rigorous analytical testing to ensure high purity, specific activity, and functional consistency. Certificates of Analysis (COA) detailing assay results, purity, and stability are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and activity.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Conforms
Specific Activity	≥ [Value] units/mg protein
Purity (SDS-PAGE)	≥ 90%
Protein Content (Biuret)	Reported on COA
pH (in solution)	6.0 - 8.0
Endotoxin (LAL)	< 1.0 EU/µg
Biological Activity	Confirmed by substrate cleavage

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.