Description

Cytochrome p-448 CAS NO 9035-50-1 is a critical enzyme belonging to the cytochrome P450 superfamily, specifically known for its role in the metabolism of xenobiotics and certain endogenous compounds. This product is essential for researchers and manufacturers requiring a high-purity, biologically active enzyme for metabolic studies and biochemical applications. It is primarily utilized in pharmaceutical R&D, toxicology screening, and academic research focused on drug metabolism and enzyme kinetics.

Application

• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used as a key reagent in in vitro assays to predict drug-drug interactions and metabolic pathways.
• Toxicological Screening: Employed in research to assess the bioactivation of procarcinogens and other toxic compounds.
• Enzyme Characterization: Serves as a standard or substrate in studies aimed at understanding cytochrome P450 enzyme structure, function, and inhibition.
• Biochemical Research: Utilized in academic and industrial laboratories for investigating phase I metabolism and oxidative reactions.
• Diagnostic Kit Development: Acts as a component in the development of diagnostic assays for metabolic enzyme activity.

Basic Information

Product Name	Cytochrome p-448
CAS No.	9035-50-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cytochrome P448; CYP1A1; Aryl Hydrocarbon Hydroxylase; Benzo[a]pyrene Hydroxylase; Cytochrome P-450c; Cytochrome P450 1A1; Microsomal cytochrome P-448; P-448; EC 1.14.14.1
EINECS	Contact for details

Quality Control

Our Cytochrome p-448 is produced and tested under stringent quality protocols to ensure high biological activity and purity suitable for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as specific activity, protein content, and purity. We adhere to relevant quality management standards to guarantee supply reliability and batch-to-batch consistency for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under appropriate conditions to minimize exposure to atmospheric moisture. For optimal performance, avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Specific Activity	Contact for details
Protein Content (Bradford)	≥ Contact for details
Purity (SDS-PAGE)	≥ Contact for details
Solubility	Soluble in appropriate aqueous buffers
Storage Buffer	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.