Description

Orotidine-5'-Monophosphate*Pyrophosphorylase From Br is a highly purified enzyme preparation derived from a bacterial source, specifically catalyzing the conversion of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). This enzyme is a critical reagent in biochemical research and diagnostic applications for studying pyrimidine biosynthesis pathways. It is essential for researchers and manufacturers in the fields of enzymology, molecular biology, and pharmaceutical development who require reliable, high-activity enzyme components.

Application

• Biochemical Research: Used as a key reagent in enzymatic assays to study the pyrimidine de novo biosynthesis pathway and enzyme kinetics.
• Diagnostic Kit Manufacturing: Incorporated into in-vitro diagnostic (IVD) kits for the detection and quantification of related metabolites or enzyme activities in clinical samples.
• Pharmaceutical Development: Serves as a tool enzyme for screening potential inhibitors targeting the UMP synthase complex for drug discovery applications.
• Enzyme Production & Purification Studies: Used as a standard or reference material in downstream process development for recombinant enzyme purification.
• Academic & Educational Use: Employed in university and institutional laboratories for teaching advanced concepts in metabolism and enzymology.

Basic Information

Product Name	Orotidine-5'-Monophosphate*Pyrophosphorylase From Br
CAS No.	9030-25-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Orotidine-5'-phosphate decarboxylase; OMP Decarboxylase; Orotidine 5'-monophosphate decarboxylase; UMP synthase (multifunctional enzyme complex); Orotidine-5'-monophosphate pyrophosphorylase/decarboxylase; Pyr5,6; OMPDCase; EC 4.1.1.23 (component activity)
EINECS	Contact for details

Quality Control

Our enzyme preparations are produced and tested under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high specific activity, purity, and stability. Quality parameters typically assessed include protein concentration, specific activity (U/mg), and absence of contaminating nucleases or proteases. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation. Aliquot into working volumes upon first use to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Specific Activity	≥ [Value] units/mg protein
Protein Content (Bradford)	≥ [Value] mg/mL
Purity (SDS-PAGE)	≥ [Value] %
Contaminants (DNase/RNase)	Not detected
pH (in solution)	7.0 - 7.5
Buffer Composition	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.