Description

Mitochondrial CAS NO 9028-80-2 is a high-purity biochemical reagent, specifically a mitochondrial preparation derived from biological sources. This product is essential for research and development in cellular metabolism, bioenergetics, and mitochondrial function studies. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in metabolic pathway analysis and drug discovery.

Application

• Cellular Metabolism Research: Used as a critical substrate for studying oxidative phosphorylation, ATP production, and electron transport chain activity in vitro.
• Drug Discovery & Toxicology Screening: Employed in high-throughput assays to evaluate the effects of novel compounds on mitochondrial function and to identify potential mitochondrial toxins.
• Bioenergetics Studies: Serves as a fundamental tool for measuring oxygen consumption rates (OCR) and assessing cellular metabolic flux using instruments like Seahorse Analyzers.
• Enzymology: Provides a source for the isolation and study of mitochondrial-specific enzymes involved in the Krebs cycle and fatty acid oxidation.
• Diagnostic Development: Used in the research and development of diagnostic kits for mitochondrial disorders and metabolic diseases.
• Nutritional & Supplement Research: Applied in studies investigating the impact of nutrients, antioxidants, and other bioactive compounds on mitochondrial health and efficiency.

Basic Information

Item	Details
Product Name	Mitochondrial CAS NO 9028-80-2
CAS No.	9028-80-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Mitochondrial Fraction; Mitochondrial Preparation; Liver Mitochondria; Heart Mitochondria; Mitochondrial Extract; Mitochondrial Suspension; Isolated Mitochondria; Submitochondrial Particles
EINECS	Contact for details

Quality Control

Our Mitochondrial preparations undergo rigorous quality testing to ensure batch-to-batch consistency, functional activity, and purity. Each lot is characterized for protein content, specific enzymatic activity (e.g., citrate synthase), and membrane integrity. Certificates of Analysis (COA) detailing these parameters are available upon request to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store frozen at -70°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. Thaw on ice immediately before use.

Specification

Item	Specification
Appearance	Off-white to light brown suspension
Protein Concentration	10 - 50 mg/mL (Bradford or BCA assay)
Citrate Synthase Activity	> 100 nmol/min/mg protein
Respiratory Control Ratio (RCR)	> 3 (with Pyruvate/Malate)
Purity (by SDH Activity)	> 90% mitochondrial
Endotoxin Level	< 1.0 EU/mg protein (LAL test)
Viability (by MTT Assay)	> 85%
Storage Buffer	Sucrose-based isolation medium

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.