Description

Ec 1.1.1.18, also known as myo-inositol oxygenase, is a crucial enzyme in the inositol catabolic pathway. Its primary function is to catalyze the cleavage of myo-inositol into D-glucuronate, a key step in the metabolism of inositol phosphates and phosphatidylinositol signaling molecules. This enzyme is essential for research and development in biochemistry, molecular biology, and pharmaceutical discovery, particularly in studies related to cellular signaling, metabolic disorders, and drug target identification. It is supplied as a high-purity, lyophilized powder suitable for laboratory and industrial biocatalytic applications.

Application

• Biochemical Research: Used as a critical reagent for studying the inositol phosphate metabolic pathway and its role in cellular signal transduction.
• Enzymology Studies: Employed in kinetic assays and mechanism-of-action studies to understand substrate specificity and catalytic efficiency.
• Pharmaceutical Development: Serves as a potential target enzyme for drug discovery programs focused on metabolic diseases and conditions linked to inositol dysregulation.
• Diagnostic Kit Manufacturing: Incorporated as a component in enzymatic assay kits for the quantitative determination of myo-inositol levels in clinical and research samples.
• Biocatalysis: Utilized in specialized synthetic pathways for the production of D-glucuronate or related sugar acids.
• Academic & Industrial R&D: A fundamental tool for laboratories investigating plant biology, neurochemistry, and yeast genetics where inositol metabolism is pivotal.

Basic Information

Product Name	Ec 1.1.1.18
CAS No.	9028-25-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Myo-inositol oxygenase; MIOX; Inositol oxygenase; EC 1.1.1.18; myo-Inositol:oxygen oxidoreductase; 1D-myo-inositol oxygenase; Inositol dehydrogenase (misleading); CAS 9028-25-5
EINECS	Contact for details

Quality Control

Our Ec 1.1.1.18 is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high specific activity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing key parameters such as protein concentration, specific activity, and purity profile via SDS-PAGE. We adhere to relevant quality standards suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption. For extended storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Activity)	Conforms (Specific activity provided on COA)
Protein Content (Bradford)	>90%
Purity (SDS-PAGE)	>95%
Specific Activity	≥ [Value] units/mg protein
Solubility	Soluble in appropriate buffer
pH (in solution)	7.0 - 7.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.