Description

2-Deoxy-D-Ribose 5-Phosphate Aldolase E is a highly specific enzyme that catalyzes the reversible aldol condensation of acetaldehyde and D-glyceraldehyde 3-phosphate to form 2-deoxy-D-ribose 5-phosphate, a key intermediate in nucleotide biosynthesis. This biocatalyst is essential for research and development in enzymatic synthesis and metabolic pathway studies, offering high selectivity and efficiency under mild conditions. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in nucleotide chemistry, enzymology, and the development of novel biochemical assays.

Application

• Enzymatic Synthesis: Key catalyst for the in vitro production of 2-deoxy-D-ribose 5-phosphate and related nucleotide precursors.
• Biochemical Research: Fundamental tool for studying the non-oxidative pentose phosphate pathway and deoxyribose metabolism.
• Pharmaceutical R&D: Used in the development and screening of potential enzyme inhibitors targeting nucleotide biosynthesis for therapeutic applications.
• Diagnostic Kit Manufacturing: Component in specialized diagnostic assays and kits for metabolic disorder research.
• Biocatalysis Process Development: Employed in the design of green chemistry and biocatalytic routes for fine chemical production.
• Academic & Teaching Laboratories: Used for educational purposes in advanced biochemistry and molecular biology courses.

Basic Information

Product Name	2-Deoxy-D-Ribose 5-Phosphate Aldolase E
CAS No.	9026-97-5
Molecular Formula	N/A (Enzyme)
Molecular Weight	Varies by preparation (Contact for details)
Synonyms	DERA; 2-Deoxyribose-5-phosphate aldolase; Deoxyriboaldolase; 2-Deoxy-D-ribose-5-phosphate acetaldehyde-lyase; EC 4.1.2.4; Aldolase, 2-deoxyribose-5-phosphate; 2-Deoxyribose 5-phosphate aldolase E.
EINECS	Contact for details

Quality Control

Our 2-Deoxy-D-Ribose 5-Phosphate Aldolase E is produced and tested under stringent quality management systems. Each lot is characterized for specific activity, purity, and stability to ensure reproducible performance in research and industrial applications. Certificates of Analysis (COA) detailing activity units, protein content, and purity assessments are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This material is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation. Aliquot reconstituted solutions to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Specific Activity	≥ [Value] units/mg protein
Protein Content (Biuret)	≥ [Value] %
Purity (SDS-PAGE)	≥ [Value] %
Identification (Activity)	Conforms
pH (in solution)	7.0 - 7.5
Endotoxin (LAL)	< [Value] EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.