Description

Atp:(D)Gmp Phosphotransferase is a specialized enzyme that catalyzes the transfer of a phosphate group from adenosine triphosphate (ATP) to dGMP, playing a crucial role in nucleotide metabolism. This enzymatic activity is vital for researchers and manufacturers involved in the synthesis and study of nucleotide analogs and nucleic acid biochemistry. It is an essential reagent for biotechnology, pharmaceutical research, and diagnostic kit development, where precise enzymatic control is required. The product is supplied with a high level of purity and activity to ensure reliable and reproducible results in demanding applications.

Application

• Biochemical Research: A key tool for studying nucleotide salvage pathways, enzyme kinetics, and phosphorylation mechanisms in vitro.
• Pharmaceutical Development: Used in the synthesis and screening of novel nucleotide-based prodrugs and antiviral agents.
• Diagnostic Manufacturing: Incorporated as a critical component in enzymatic assay kits for clinical diagnostics and life science research.
• Enzymology Studies: Serves as a model enzyme for investigating phosphotransferase family structure, function, and inhibition.
• Biocatalysis: Potential application in the enzymatic synthesis of specific phosphorylated nucleotides under controlled conditions.

Basic Information

Product Name	Atp:(D)Gmp Phosphotransferase
CAS No.	9026-59-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	ATP:dGMP Phosphotransferase; Deoxyguanylate Kinase; dGMP Kinase; Nucleoside-Phosphate Kinase (EC 2.7.4.8); ATP:Deoxyguanylate Phosphotransferase; Guanylate Kinase (dGMP-specific); 2.7.4.8; ATP:dGMP phosphotransferase (phosphorylating)
EINECS	Contact for details

Quality Control

Our Atp:(D)Gmp Phosphotransferase is produced and tested under stringent quality management systems. Each batch is characterized for specific activity, purity, and absence of contaminating nucleases and phosphatases. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as protein concentration, activity units, and purity assessed by SDS-PAGE. We adhere to relevant guidelines for enzyme production to ensure consistent performance and reliability for your critical research and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in a non-frost-free freezer. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. Aliquot into working volumes upon first use to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Conforms
Specific Activity	≥ [Value] units/mg protein
Purity (SDS-PAGE)	≥ 90%
Protein Concentration	Provided on COA
pH (in solution)	7.0 - 7.5
Endotoxin	< 1.0 EU/μg (if applicable)
Storage Buffer	Specified on label

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.