Description

Cam Kinase Ii CAS NO 9026-43-1 is a highly purified calcium/calmodulin-dependent protein kinase II enzyme, a critical regulator of signal transduction pathways. This product is essential for biochemical research, enabling the study of cellular processes related to memory, cardiac function, and neuronal signaling. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic manufacturers for enzyme assays, drug discovery, and the development of screening kits.

Application

• Biochemical Research & Assay Development: Used as a key reagent in kinase activity assays to study phosphorylation mechanisms and signal transduction.
• Drug Discovery & Screening: Employed in high-throughput screening (HTS) platforms to identify and validate novel kinase inhibitors for therapeutic development.
• Diagnostic Kit Manufacturing: Serves as a critical component in the production of ELISA kits and other diagnostic reagents for research and clinical analysis.
• Academic & Pharmaceutical R&D: Facilitates fundamental research into neurological disorders, cardiac diseases, and cellular metabolism.
• Enzyme Characterization Studies: Used to investigate enzyme kinetics, substrate specificity, and the effects of modulators on CaMKII activity.

Basic Information

Product Name	Cam Kinase Ii
CAS No.	9026-43-1
Molecular Formula	Protein
Molecular Weight	Variable (Multimeric complex ~300-600 kDa)
Synonyms	CaMKII; Calcium/Calmodulin-Dependent Protein Kinase Type II; CaM Kinase II; CaMK2; EC 2.7.11.17; Multifunctional Ca2+/Calmodulin-dependent Protein Kinase; CaM-Kinase II; Ca2+/Calmodulin-dependent Protein Kinase II
EINECS	Contact for details

Quality Control

Our Cam Kinase Ii is produced under stringent conditions to ensure high activity, purity, and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including activity assays, purity assessment via SDS-PAGE, and specificity checks. A detailed Certificate of Analysis (COA) documenting purity, specific activity, and storage buffer composition is provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in aliquots to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Keep the enzyme in the recommended storage buffer upon receipt.

Specification

Item	Specification
Appearance	Clear to slightly opalescent liquid
Identification (Activity)	Conforms
Specific Activity	≥ XXXX units/mg protein (Lot-specific)
Purity (SDS-PAGE)	≥ 90%
Protein Concentration	XX mg/mL (Lot-specific)
Storage Buffer	Tris-HCl, Glycerol, DTT, EDTA
Endotoxin Level	< 1.0 EU/μg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.