Description

Histidase is a crucial enzyme, also known as histidine ammonia-lyase, which catalyzes the first step in the degradation of the essential amino acid L-histidine. This product is vital for research and development in biochemistry, enzymology, and metabolic studies. It is primarily used by pharmaceutical researchers, diagnostic kit manufacturers, and academic institutions focused on inborn errors of metabolism, such as histidinemia.

Application

• Biochemical Research: Used as a model enzyme for studying enzyme kinetics, reaction mechanisms, and ammonia-lyase activity.
• Diagnostic Reagents: A key component in enzymatic assay kits for the quantitative determination of L-histidine in biological samples.
• Metabolic Disorder Studies: Essential for in-vitro research related to histidinemia, a rare autosomal recessive metabolic disorder.
• Pharmaceutical Development: Employed in screening and development of potential modulators or inhibitors for therapeutic applications.
• Enzyme Immobilization Studies: Used in research for developing immobilized enzyme systems for biotechnological processes.
• Food & Nutrition Analysis: Applied in methods for analyzing histidine content in foodstuffs and nutritional supplements.

Basic Information

Product Name	Histidase
CAS No.	9013-75-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Histidine Ammonia-Lyase; Histidinase; L-Histidine Ammonia-Lyase; HAL; EC 4.3.1.3; Histidine α-deaminase; L-Histidine deaminase
EINECS	Contact for details

Quality Control

Our Histidase is produced and tested under stringent quality management protocols to ensure high purity and consistent enzymatic activity. Each batch is characterized for specific activity and purity profile. A comprehensive Certificate of Analysis (COA) detailing assay, purity, and stability is provided with every shipment to guarantee it meets your research and application specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (IR)	Conforms
Specific Activity	≥ 0.5 units/mg protein
Protein Content (Biuret)	≥ 80%
Solubility	Soluble in water or buffer
Loss on Drying	≤ 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.