Description

Homocysteine Methyltransferase, Recombinant is a high-purity, catalytically active enzyme produced through advanced recombinant DNA technology. This product is essential for biochemical research and diagnostic applications involving sulfur amino acid metabolism, particularly the remethylation of homocysteine to methionine. It is a critical reagent for pharmaceutical R&D, clinical diagnostics, and academic studies focused on cardiovascular health, metabolic disorders, and methylation cycle analysis.

Application

• Biochemical Research & Assay Development: Used as a key component in enzymatic assays to study homocysteine metabolism, methylation pathways, and enzyme kinetics.
• Diagnostic Kit Manufacturing: Serves as a core reactive enzyme in clinical diagnostic kits for the quantitative measurement of homocysteine, S-adenosylmethionine (SAM), or related metabolites in serum/plasma.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and evaluate potential drug candidates that modulate methyltransferase activity for therapeutic intervention.
• Metabolic Pathway Analysis: Facilitates in vitro studies of the methionine cycle and its link to folate and vitamin B12 metabolism in cell culture and tissue models.
• Enzyme Replacement & Protein Engineering Studies: Provides a standardized, recombinant enzyme source for functional studies, structural analysis, and protein engineering projects.
• Quality Control Reference Standard: Acts as a reference material for calibrating diagnostic equipment and validating assay performance in quality control laboratories.

Basic Information

Item	Details
Product Name	Homocysteine Methyltransferase, Recombinant
CAS No.	9012-40-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HMTase, Recombinant; Betaine-Homocysteine S-Methyltransferase (BHMT); Recombinant Homocysteine Methyltransferase; EC 2.1.1.5 (Recombinant); Homocysteine Methylase; Recombinant Methyltransferase; S-Methylmethionine-Homocysteine Methyltransferase; Recombinant Enzyme 9012-40-2
EINECS	Contact for details

Quality Control

Our recombinant Homocysteine Methyltransferase is produced under stringent conditions to ensure batch-to-batch consistency and high specific activity. Each lot undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, activity assays, and endotoxin level checks. A Certificate of Analysis (COA) detailing purity, activity (U/mg), and storage buffer composition is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent moisture absorption and activity loss.

Specification

Item	Specification
Appearance	Clear to slightly opalescent solution
Purity (SDS-PAGE)	≥ 90%
Specific Activity	≥ XX U/mg protein
Protein Concentration	XX mg/mL
Buffer Composition	XX mM Tris-HCl, XX mM NaCl, pH X.X, XX% Glycerol
Endotoxin Level	< 1.0 EU/μg
Identification (Activity)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.