Description

Piperazine-N,N'-Bis-(2-Ethanesulphonic Acid) Dipotassium Salt is a high-purity biochemical buffer salt, essential for maintaining precise pH stability in sensitive biological and chemical systems. Its primary value lies in its excellent buffering capacity in the physiological pH range, making it a critical reagent for research and industrial processes requiring controlled ionic strength and pH. This product is particularly needed by manufacturers and researchers in the biotechnology, pharmaceutical, and diagnostic sectors for applications such as cell culture media preparation, enzyme assays, and electrophoresis.

Application

• Biochemical Buffering Agent: Used in the preparation of cell culture media, lysis buffers, and electrophoresis running buffers to maintain stable pH conditions.
• Pharmaceutical Intermediates: Serves as a key component or buffer in the synthesis and formulation of active pharmaceutical ingredients (APIs) and diagnostic reagents.
• Molecular Biology Research: Essential for nucleic acid purification protocols, PCR master mixes, and various enzyme reaction buffers where consistent ionic strength is required.
• Protein Chemistry: Employed in protein purification, crystallization, and stability studies to prevent pH-induced denaturation.
• Diagnostic Kits: Incorporated into the formulation of clinical diagnostic assays and kits to ensure assay reproducibility and accuracy.
• Industrial Bioprocessing: Used as a buffering component in fermentation processes and downstream purification steps in biomanufacturing.

Basic Information

Product Name	Piperazine-N,N'-Bis-(2-Ethanesulphonic Acid) Dipotassium Salt
CAS No.	108321-27-3
Molecular Formula	C10H18K2N2O6S2
Molecular Weight	428.59 g/mol
Synonyms	PIPES Dipotassium Salt; 1,4-Piperazinediethanesulfonic Acid Dipotassium Salt; Piperazine-1,4-bis(2-ethanesulfonic acid) Dipotassium Salt; Dipotassium PIPES; PIPES Dipotassium; Dipotassium Piperazine-1,4-bis(2-ethanesulfonate); Dipotassium 1,4-Piperazinediethanesulfonate; PIPES K2 Salt
EINECS	Contact for details

Quality Control

Our Piperazine-N,N'-Bis-(2-Ethanesulphonic Acid) Dipotassium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and industrial applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every lot upon request, providing full traceability and quality assurance for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
pH (1% Solution)	6.5 - 7.5
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 10 ppm
Endotoxin (LAL)	< 0.1 EU/mg (for applicable grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.