Description

Deoxyribonuclease CAS NO 9003-98-9 is a hydrolytic enzyme that specifically cleaves the phosphodiester bonds in DNA. This product is critical for applications requiring the removal or digestion of DNA to prevent contamination, improve sample purity, or study nucleic acid structure. It is an essential reagent for biotechnology, pharmaceutical research, and molecular biology laboratories.

Application

• Biopharmaceutical Manufacturing: Used to reduce viscosity and remove host cell DNA during downstream purification of protein-based therapeutics.
• Molecular Biology Research: Essential for DNA footprinting assays, preparing RNA samples free of genomic DNA contamination, and various nucleic acid manipulation protocols.
• Cell Culture & Diagnostics: Employed in cell dissociation protocols and as a component in certain diagnostic kits to eliminate interfering DNA.
• Forensic Science: Applied in sample preparation to degrade non-target DNA, aiding in the analysis of specific genetic material.
• Food Safety Testing: Utilized in nucleic acid-based pathogen detection methods to prepare samples and ensure assay accuracy.

Basic Information

Product Name	Deoxyribonuclease
CAS No.	9003-98-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	DNase I; Deoxyribonuclease I; Pancreatic Dornase; Streptodornase; DNAase; Endonuclease; Deoxyribonucleate 5'-oligonucleotidohydrolase
EINECS	Contact for details

Quality Control

Our Deoxyribonuclease is produced and tested under a rigorous quality management system. Each batch is analyzed for key parameters including enzymatic activity, purity, and the absence of contaminating RNase and protease activities. Certificates of Analysis (COA) detailing these specifications are available upon request to ensure compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms
Activity (Kunitz Units/mg)	> 2,000
Protein Content (Biuret)	> 90%
RNase Activity	Not detected
Protease Activity	Not detected
pH (in solution)	6.0 - 7.5
Loss on Drying	< 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.