Description

Succinate Dehydrogenase CAS NO 9002-02-2 is a critical enzyme complex (Complex II) involved in both the citric acid cycle and the mitochondrial electron transport chain. Its primary function is to catalyze the oxidation of succinate to fumarate, making it an essential component for cellular respiration and energy production. This high-purity enzyme is indispensable for researchers and manufacturers in life sciences, diagnostics, and pharmaceutical development, particularly for metabolic studies and enzyme-linked assay systems.

Application

• Biochemical Research & Metabolic Studies: Used as a key reagent for investigating the Krebs cycle, mitochondrial function, and cellular bioenergetics.
• Diagnostic Kit Manufacturing: Serves as a critical component in clinical diagnostic kits for measuring succinate or related metabolites.
• Pharmaceutical Development: Employed in drug discovery and screening assays targeting mitochondrial dysfunction and metabolic diseases.
• Enzyme Activity Assays: Acts as a standard or active ingredient in commercial assay kits for determining succinate dehydrogenase activity.
• Academic & Industrial Enzymology: Utilized for studying enzyme kinetics, inhibition, and structure-function relationships.
• Food & Beverage Analysis: Applied in enzymatic methods for the quantification of succinic acid or related compounds in quality control labs.

Basic Information

Product Name	Succinate Dehydrogenase
CAS No.	9002-02-2
Molecular Formula	N/A (Enzyme Complex)
Molecular Weight	Varies by source and subunit composition
Synonyms	Succinate Dehydrogenase Complex; SDH; Succinate:ubiquinone oxidoreductase; Mitochondrial Complex II; Flavoprotein subunit of Complex II; EC 1.3.5.1; Succinate-CoQ Reductase; Succinic Dehydrogenase
EINECS	Contact for details

Quality Control

Our Succinate Dehydrogenase is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and high specific activity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as activity units, protein content, and purity. We adhere to relevant guidelines for enzyme preparation, ensuring suitability for research and in-vitro diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). Avoid repeated freeze-thaw cycles. For specific storage and handling instructions of your ordered grade, please refer to the accompanying technical data sheet.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Conforms
Specific Activity	> [Value] units/mg protein
Protein Content (Biuret)	> [Value] %
Purity (SDS-PAGE)	> [Value] %
Solubility	Clear, slightly colored solution
pH (in solution)	7.0 - 7.5
Microbial Limits	Meets specification for biological products

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.