Description

Creatine Phosphokinase is a crucial enzyme that catalyzes the reversible transfer of a phosphate group between creatine and adenosine triphosphate (ATP), playing a fundamental role in cellular energy metabolism. Its reliable activity and purity are essential for accurate diagnostic and research applications, where consistency directly impacts results. This product is primarily needed by manufacturers of in-vitro diagnostic (IVD) kits, clinical biochemistry laboratories, and life science research institutions focused on cardiac, muscular, and neurological studies.

Application

• Clinical Diagnostics: A key reagent component in commercial test kits and automated analyzers for measuring serum creatine kinase (CK) levels, aiding in the diagnosis of myocardial infarction, muscular dystrophy, and other tissue damage.
• Biochemical Research: Used as a model enzyme in studies of enzyme kinetics, energy metabolism pathways (creatine phosphate shuttle), and muscle physiology.
• Quality Control & Calibration: Serves as a reference standard or calibrator for validating the performance of diagnostic assays and laboratory equipment.
• Pharmaceutical Development: Employed in research investigating therapeutic interventions for conditions involving energy metabolism dysfunction.

Basic Information

Product Name	Creatine Phosphokinase
CAS No.	9001-15-4
Molecular Formula	N/A (Enzyme)
Molecular Weight	~86 kDa (Dimer)
Synonyms	Creatine Kinase; CK; ATP:Creatine N-Phosphotransferase; CPK; Adenosine Triphosphate-Creatine Phosphotransferase; Creatine Phosphotransferase
EINECS	232-590-8

Quality Control

Our Creatine Phosphokinase is manufactured and tested under a rigorous quality management system. Each lot is characterized for critical parameters including specific activity, purity, and stability to ensure performance consistency for diagnostic and research use. A comprehensive Certificate of Analysis (COA) detailing assay results, including activity units (U/mg) and impurity profiles, is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This material is hygroscopic (moisture-sensitive). For long-term stability, keep the desiccant in the original container and avoid frequent temperature fluctuations.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or suspension
Identification (IR/Activity)	Conforms
Specific Activity	≥ 150 U/mg protein
Protein Content (Biuret)	Contact for details
Purity (SDS-PAGE)	≥ 90%
Solubility	Clear solution in buffer
Loss on Drying	≤ 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.