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1,2-Dimyristoyl-Sn-Glycero-3-Phosphoethanolamine CAS NO 998-07-2


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CAS No.:998-07-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Dimyristoyl-Sn-Glycero-3-Phosphoethanolamine is a high-purity, synthetic phospholipid belonging to the phosphatidylethanolamine (PE) class, widely recognized for its role as a critical building block in advanced lipid-based formulations. This compound is essential for creating stable, biocompatible membranes and vesicles, making it invaluable for research and development in cutting-edge delivery systems. It is primarily sought after by scientists and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries for applications in liposome preparation, drug delivery, and membrane biophysics studies.

Application

  • Liposome and Nanoparticle Formulation: A key structural lipid for creating unilamellar and multilamellar vesicles for drug encapsulation and targeted delivery systems.
  • Drug Delivery Research: Used in the development of lipid nanoparticles (LNPs) for mRNA, siRNA, and other nucleic acid therapeutics.
  • Membrane Biophysics Studies: Serves as a model membrane component to study lipid bilayer properties, fusion, and protein-lipid interactions.
  • Cosmetic & Dermal Applications: Incorporated into advanced cosmetic formulations like niosomes and transfersomes for enhanced skin penetration and active ingredient stability.
  • Diagnostic Reagents: Used in the preparation of lipid-based reagents for diagnostic assays and biosensors.
  • Biomimetic Coatings: Applied in surface modification to create biocompatible, cell-mimicking coatings for medical devices and implants.

Basic Information

Product Name 1,2-Dimyristoyl-Sn-Glycero-3-Phosphoethanolamine
CAS No. 998-07-2
Molecular Formula C33H66NO8P
Molecular Weight 635.85 g/mol
Synonyms DMPE; 1,2-Dimyristoylphosphatidylethanolamine; DMPE (14:0/14:0); PE(14:0/14:0); 1,2-Ditetradecanoyl-sn-glycero-3-phosphoethanolamine; Phosphatidylethanolamine, 1,2-dimyristoyl-; (2R)-2,3-Bis(tetradecanoyloxy)propyl 2-aminoethyl phosphate; DMPC (Note: DMPC is a common but incorrect synonym for the choline version; included here for search relevance clarification).
EINECS 213-637-2

Quality Control

Our 1,2-Dimyristoyl-Sn-Glycero-3-Phosphoethanolamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive) and easily oxidized; therefore, it should be handled in a dry environment and allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Melting Point Contact for details
Loss on Drying ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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