Description

Difenidol is a versatile pharmaceutical intermediate and active ingredient with significant applications in medicinal chemistry. Its primary value lies in its role as a key building block for synthesizing compounds that affect the central nervous system, particularly those with antiemetic and antivertigo properties. This makes it a critical raw material for manufacturers in the pharmaceutical industry developing treatments for motion sickness, nausea, and balance disorders. The compound is supplied under stringent quality controls to ensure consistency and reliability for industrial-scale synthesis.

Application

• Pharmaceutical Active Ingredient: Primary use as the active pharmaceutical ingredient (API) in formulations for treating vertigo and associated nausea.
• Antiemetic Drug Synthesis: Key intermediate in the production of medications designed to prevent and treat nausea and vomiting.
• Central Nervous System (CNS) Research: Used in R&D laboratories for studying vestibular system disorders and developing novel therapeutic agents.
• Veterinary Medicine: Employed in the formulation of veterinary pharmaceuticals for motion sickness in animals.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical manufacturing.

Basic Information

Product Name	Difenidol
CAS No.	972-02-1
Molecular Formula	C21H27NO
Molecular Weight	309.45 g/mol
Synonyms	α,α-Diphenyl-1-piperidinebutanol; 1,1-Diphenyl-4-piperidino-1-butanol; Diphenidol; Cephadol; Vontrol; Difenidol Hydrochloride (salt form); SKF 478
EINECS	213-537-8

Quality Control

Our Difenidol is manufactured and tested under a strict quality management system to ensure it meets the high standards required for pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to current Good Manufacturing Practices (cGMP) principles, and our quality protocols are designed to support regulatory filings in major global markets, including those governed by the FDA and EMA.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.